Machine learning and semi-targeted lipidomics identify distinct serum lipid signatures in hospitalized COVID-19-positive and COVID-19-negative patients

H Castañé, S Iftimie, G Baiges-Gaya… - Metabolism, 2022 - Elsevier
Background Lipids are involved in the interaction between viral infection and the host
metabolic and immunological responses. Several studies comparing the lipidome of COVID …

[HTML][HTML] Diagnostic potential of the plasma lipidome in infectious disease: application to acute SARS-CoV-2 infection

N Gray, NG Lawler, AX Zeng, M Ryan, SH Bong… - Metabolites, 2021 - mdpi.com
Improved methods are required for investigating the systemic metabolic effects of SARS-
CoV-2 infection and patient stratification for precision treatment. We aimed to develop an …

[HTML][HTML] Metabolic and lipidomic markers differentiate COVID-19 from non-hospitalized and other intensive care patients

F Schmelter, B Föh, A Mallagaray… - Frontiers in Molecular …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a viral infection affecting multiple organ systems of
great significance for metabolic processes. Thus, there is increasing interest in metabolic …

[HTML][HTML] Link between serum lipid signature and prognostic factors in COVID-19 patients

M Dei Cas, S Ottolenghi, C Morano, R Rinaldo… - Scientific Reports, 2021 - nature.com
Although the serum lipidome is markedly affected by COVID-19, two unresolved issues
remain: how the severity of the disease affects the level and the composition of serum lipids …

Lipidomic alteration of plasma in cured COVID-19 patients using ultra high-performance liquid chromatography with high-resolution mass spectrometry

Y Bai, W Huang, Y Li, C Lai, S Huang… - Bioscience …, 2021 - portlandpress.com
Background: The pandemic of novel coronavirus disease 2019 (COVID-19) has become a
serious public health crisis worldwide. The symptoms of COVID-19 vary from mild to severe …

[HTML][HTML] Untargeted analysis in post-COVID-19 patients reveals dysregulated lipid pathways two years after recovery

Y López-Hernández, JJ Oropeza-Valdez… - Frontiers in molecular …, 2023 - frontiersin.org
Introduction: Similar to what it has been reported with preceding viral epidemics (such as
MERS, SARS, or influenza), SARS-CoV-2 infection is also affecting the human …

Untargeted lipidomics reveals specific lipid profiles in COVID-19 patients with different severity from Campania region (Italy)

M Ciccarelli, F Merciai, A Carrizzo, E Sommella… - … of Pharmaceutical and …, 2022 - Elsevier
COVID-19 infection evokes various systemic alterations that push patients not only towards
severe acute respiratory syndrome but causes an important metabolic dysregulation with …

[HTML][HTML] Serum lipid mediator profiles in COVID-19 patients and lung disease severity: a pilot study

P Irún, R Gracia, E Piazuelo, J Pardo, E Morte… - Scientific Reports, 2023 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is highly
heterogeneous, ranging from asymptomatic to severe and fatal cases. COVID-19 has been …

[PDF][PDF] Distinct lipid metabolic dysregulation in asymptomatic COVID-19

Y Hao, Z Zhang, G Feng, M Chen, Q Wan, J Lin, L Wu… - Iscience, 2021 - cell.com
Asymptomatic infection is a big challenge in curbing the spread of COVID-19. However, its
identification and pathogenesis elucidation remain issues. Here, by performing …

[HTML][HTML] Dysregulation of lipid metabolism and pathological inflammation in patients with COVID-19

M Caterino, M Gelzo, S Sol, R Fedele, A Annunziata… - Scientific reports, 2021 - nature.com
In recent months, Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world. COVID-19 …