Liver fatty acid-binding protein and obesity
BP Atshaves, GG Martin, HA Hostetler… - The Journal of nutritional …, 2010 - Elsevier
While low levels of unesterified long chain fatty acids (LCFAs) are normal metabolic
intermediates of dietary and endogenous fat, LCFAs are also potent regulators of key …
intermediates of dietary and endogenous fat, LCFAs are also potent regulators of key …
Hepatic phenotype of liver fatty acid binding protein gene-ablated mice
GG Martin, BP Atshaves, H Huang… - American Journal …, 2009 - journals.physiology.org
Although the function of liver fatty acid binding protein in hepatic fatty acid metabolism has
been extensively studied, its potential role in hepatic cholesterol homeostasis is less clear …
been extensively studied, its potential role in hepatic cholesterol homeostasis is less clear …
[PDF][PDF] Protection against Western diet–induced obesity and hepatic steatosis in liver fatty acid–binding protein knockout mice
EP Newberry, Y Xie, SM Kennedy, J Luo… - …, 2006 - Wiley Online Library
Liver fatty acid–binding protein (L‐Fabp) regulates murine hepatic fatty acid trafficking in
response to fasting. In this study, we show that L‐Fabp−/− mice fed a high‐fat Western diet …
response to fasting. In this study, we show that L‐Fabp−/− mice fed a high‐fat Western diet …
[HTML][HTML] Decreased hepatic triglyceride accumulation and altered fatty acid uptake in mice with deletion of the liver fatty acid-binding protein gene
EP Newberry, Y Xie, S Kennedy, X Han… - Journal of Biological …, 2003 - ASBMB
Liver fatty acid-binding protein (L-Fabp) is an abundant cytosolic lipid-binding protein with
broad substrate specificity, expressed in mammalian enterocytes and hepatocytes. We have …
broad substrate specificity, expressed in mammalian enterocytes and hepatocytes. We have …
Diet-induced obesity and hepatic steatosis in L-Fabp−/− mice is abrogated with SF, but not PUFA, feeding and attenuated after cholesterol supplementation
EP Newberry, SM Kennedy, Y Xie… - American Journal …, 2008 - journals.physiology.org
Liver fatty acid (FA)-binding protein (L-Fabp), a cytoplasmic protein expressed in liver and
small intestine, regulates FA trafficking in vitro and plays an important role in diet-induced …
small intestine, regulates FA trafficking in vitro and plays an important role in diet-induced …
Liver fatty acid binding protein gene ablation potentiates hepatic cholesterol accumulation in cholesterol-fed female mice
GG Martin, BP Atshaves, AL McIntosh… - American Journal …, 2006 - journals.physiology.org
Although liver fatty acid binding protein (L-FABP) is postulated to influence cholesterol
homeostasis, the physiological significance of this hypothesis remains to be resolved. This …
homeostasis, the physiological significance of this hypothesis remains to be resolved. This …
[HTML][HTML] Tissue-specific functions in the fatty acid-binding protein family
J Storch, AE Thumser - Journal of Biological Chemistry, 2010 - ASBMB
The intracellular fatty acid-binding proteins (FABPs) are abundantly expressed in almost all
tissues. They exhibit high affinity binding of a single long-chain fatty acid, with the exception …
tissues. They exhibit high affinity binding of a single long-chain fatty acid, with the exception …
Different functions of intestinal and liver-type fatty acid-binding proteins in intestine and in whole body energy homeostasis
WS Lagakos, AM Gajda, L Agellon… - American Journal …, 2011 - journals.physiology.org
It has long been known that mammalian enterocytes coexpress two members of the fatty
acid-binding protein (FABP) family, the intestinal FABP (IFABP) and the liver FABP (LFABP) …
acid-binding protein (FABP) family, the intestinal FABP (IFABP) and the liver FABP (LFABP) …
Fatty acid-binding proteins: functional understanding and diagnostic implications
H Xu, A Diolintzi, J Storch - Current Opinion in Clinical Nutrition & …, 2019 - journals.lww.com
The nine fatty acid-binding members of the FABP family have unique tissue-specific
functions and important secondary effects on tissues in which they are not expressed. For …
functions and important secondary effects on tissues in which they are not expressed. For …
The Multifunctional Family of Mammalian Fatty Acid–Binding Proteins
Fatty acid–binding proteins (FABPs) are small lipid-binding proteins abundantly expressed
in tissues that are highly active in fatty acid (FA) metabolism. Ten mammalian FABPs have …
in tissues that are highly active in fatty acid (FA) metabolism. Ten mammalian FABPs have …