High tigecycline resistance in multidrug-resistant Acinetobacter baumannii

S Navon-Venezia, A Leavitt… - Journal of Antimicrobial …, 2007 - academic.oup.com
Abstract Objectives Multidrug-resistant (MDR) Acinetobacter baumannii is increasing in our
hospital and worldwide, raising the necessity of finding effective therapies. We aimed to …

Tigecycline heteroresistance and resistance mechanism in clinical isolates of Acinetobacter baumannii

J Jo, KS Ko - Microbiology spectrum, 2021 - Am Soc Microbiol
Tigecycline is regarded as a last-resort treatment for multidrug-resistant Acinetobacter
baumannii. However, tigecycline resistance in A. baumannii has increased worldwide. In …

[HTML][HTML] In vitro activity of tigecycline in combination with various antimicrobials against multidrug resistant Acinetobacter baumannii

L Principe, S D'Arezzo, A Capone, N Petrosillo… - Annals of clinical …, 2009 - Springer
Background Infections sustained by multidrug-resistant (MDR) and pan-resistant
Acinetobacter baumannii have become a challenging problem in Intensive Care Units …

A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline

NC Gordon, DW Wareham - Journal of antimicrobial …, 2009 - academic.oup.com
Abstract Objectives Multidrug-resistant Acinetobacter baumannii (MRAB) is an increasing
problem in UK hospitals, with many strains now resistant to all available antibiotics except …

Molecular epidemiology and mechanisms of tigecycline resistance in clinical isolates of Acinetobacter baumannii from a Chinese university hospital

M Deng, MH Zhu, JJ Li, S Bi, ZK Sheng… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Because of its remarkable ability to acquire antibiotic resistance and to survive in
nosocomial environments, Acinetobacter baumannii has become a significant nosocomial …

Acinetobacter baumannii bloodstream infection while receiving tigecycline: a cautionary report

AY Peleg, BA Potoski, R Rea, J Adams… - Journal of …, 2007 - academic.oup.com
Objectives: Tigecycline has shown in vitro activity against Acinetobacter baumannii. Yet,
published clinical experience with tigecycline use outside clinical trials is lacking. We …

Comparative in vitro activities of tigecycline and 11 other antimicrobial agents against 215 epidemiologically defined multidrug-resistant Acinetobacter baumannii …

H Seifert, D Stefanik… - Journal of Antimicrobial …, 2006 - academic.oup.com
Sir, Acinetobacter baumannii is a significant nosocomial pathogen, in particular in ICU
patients. Their multidrug resistance, propensity for clonal spread and involvement in hospital …

Tigecycline Efflux as a Mechanism for Nonsusceptibility in Acinetobacter baumannii

AY Peleg, J Adams, DL Paterson - Antimicrobial agents and …, 2007 - Am Soc Microbiol
Tigecycline has an extended spectrum of in vitro antimicrobial activities, including that
against multidrug-resistant Acinetobacter. After identifying bloodstream isolates of …

Rapid Development of Acinetobacter baumannii Resistance to Tigecycline

GE Reid, SA Grim, CA Aldeza… - … : The Journal of …, 2007 - Wiley Online Library
A 53‐year‐old woman experienced a multidrug‐resistant (MDR) Acinetobacter baumannii
urinary tract infection 5 months after undergoing kidney and liver transplantation. The …

Tigecycline for the treatment of multidrug-resistant (including carbapenem-resistant) Acinetobacter infections: a review of the scientific evidence

DE Karageorgopoulos, T Kelesidis… - Journal of …, 2008 - academic.oup.com
Objectives New antibacterial agents are required for the treatment of infections caused by
multidrug-resistant (MDR) Acinetobacter spp. Whether tigecycline constitutes an effective …