Early metabolic differences between obesity-resistant and obesity-prone mice: role of adipokines
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Individually, metabolic variations can significantly influence predisposition to obesity in the
form of the obesity-prone (super-responders) and obesity-resistant (non-responders) …

Objectives Obesity is a complex disease long established to be strongly influenced by diet,
yet it is still unclear why no specific diet can effectively control obesity development across …

Aims/hypothesis Metabolic disorders are commonly investigated using knockout and
transgenic mouse models. A variety of mouse strains have been used for this purpose …

Individuals exhibit a great variation in their body weight (BW) gain response to a high fat
diet. Identification of predictive factors would enable better directed intervention toward …

Diet has a significant impact on human health, yet it is poorly represented or significantly
oversimplified in most preclinical animal studies. A majority of animals used in preclinical …

Alternate day fasting (ADF) and caloric restriction are common and effective diets for weight
loss in both rodents and humans. Weight loss is associated with improved circulating …

The sharp increase in obesity prevalence worldwide is mainly attributable to changes in
physical activity and eating behavior but the metabolic and clinical impacts of these …

Lipids are highly diverse in their composition, properties and distribution in different
biological entities. We aim to establish the lipidomes of several insulin-sensitive tissues and …

Objective Several metabolic pathways may be associated with obesity development and
may be differentially modulated by dietary constituents. The aim of this study was to access …