The involvement of natural polyphenols in molecular mechanisms inducing apoptosis in tumor cells: A promising adjuvant in cancer therapy

A Chimento, A De Luca, M D'Amico… - International Journal of …, 2023 - mdpi.com
Various literature data show how a diet rich in vegetables could reduce the incidence of
several cancers due to the contribution of the natural polyphenols contained in them …

[PDF][PDF] Natural polyphenols and apoptosis induction in cancer therapy

ML Rodríguez, JM Estrela, Á Ortega - J Carcinog Mutag S, 2013 - pdfs.semanticscholar.org
Natural polyphenols are secondary metabolites of plants involved in the defense against
different types of stress. Due to their potent antioxidant properties, polyphenols have shown …

Antiproliferative and molecular mechanism of eugenol-induced apoptosis in cancer cells

SK Jaganathan, E Supriyanto - Molecules, 2012 - mdpi.com
Phenolic phytochemicals are a broad class of nutraceuticals found in plants which have
been extensively researched by scientists for their health-promoting potential. One such a …

Kaempferol exhibits a synergistic effect with doxorubicin to inhibit proliferation, migration, and invasion of liver cancer

G Yang, J Xing, B Aikemu, J Sun… - Oncology …, 2021 - spandidos-publications.com
Kaempferol (KF), a flavonoid compound isolated from herbal medicines, has been reported
to play a significant role in inhibiting certain types of cancer. Although recent studies …

Biphasic effects of kaempferol on the estrogenicity in human breast cancer cells

SM Oh, YP Kim, KH Chung - Archives of pharmacal research, 2006 - Springer
Dietary flavonoids have attracted a great deal of attention as agents for preventing estrogen-
related diseases, such as postmenopausal symptoms, and for reducing the risk of estrogen …

Targeting apoptosis pathways in cancer and perspectives with natural compounds from mother nature

FM Millimouno, J Dong, L Yang, J Li, X Li - Cancer prevention research, 2014 - AACR
Although the incidences are increasing day after day, scientists and researchers taken
individually or by research group are trying to fight against cancer by several ways and also …

Kaempferol–A dietary anticancer molecule with multiple mechanisms of action: Recent trends and advancements

D Kashyap, A Sharma, HS Tuli, K Sak, S Punia… - Journal of functional …, 2017 - Elsevier
The consumption of diet-based naturally bioactive metabolites is preferred to synthetic
material in order to avert health-associated disorders. Among the plant-derived polyphenols …

Kaempferol inhibits VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway

H Luo, GO Rankin, N Juliano, BH Jiang, YC Chen - Food chemistry, 2012 - Elsevier
Kaempferol has been reported to reduce the risk of ovarian cancer, but the mechanism is not
completely understood. In this study, we tend to expand our understanding on how …

Chemo‐preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review

M Imran, A Rauf, ZA Shah, F Saeed… - Phytotherapy …, 2019 - Wiley Online Library
Kaempferol, a natural flavonoid present in several plants, possesses a wide range of
therapeutic properties such as antioxidant, anticancer, and anti‐inflammatory. It has a …

Kaempferol promotes apoptosis in human bladder cancer cells by inducing the tumor suppressor, PTEN

F Xie, M Su, W Qiu, M Zhang, Z Guo, B Su, J Liu… - International Journal of …, 2013 - mdpi.com
Kaempferol (Kae), a natural flavonoid, is widely distributed in fruits and vegetables. Previous
studies have identified Kae as a possible cancer preventive and therapeutic agent. We …