Apigenin induces apoptosis in human lung cancer H460 cells through caspase-and mitochondria-dependent pathways

HF Lu, YJ Chie, MS Yang, KW Lu… - Human & …, 2011 - journals.sagepub.com
Apigenin (4, 5, 7-trihydroxyflavone), a promising chemopreventive agent presented in fruits
and vegetables, has been shown to induce cell cycle arrest and apoptosis in many types of …

The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB …

RV Priyadarsini, RS Murugan, S Maitreyi… - European journal of …, 2010 - Elsevier
With increasing use of plant-derived cancer chemotherapeutic agents, exploring the
antiproliferative effects of phytochemicals has gained increasing momentum for anticancer …

Potential mechanism of phytochemical-induced apoptosis in human prostate adenocarcinoma cells: Therapeutic synergy in genistein and β-lapachone combination …

J Kumi-Diaka, S Saddler-Shawnette, A Aller… - Cancer Cell …, 2004 - Springer
Background Prostate cancer is the second leading cause of male death in the United States.
The incidence increases most rapidly with age, and multiple genetic and epigenetic factors …

Targeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer

H Yang, Q Ping Dou - Current drug targets, 2010 - ingentaconnect.com
Terpenoids represent a large and diverse class of naturally occurring compounds found in a
variety of fruits, vegetables and medicinal plants. Structurally some of the terpenoids are …

Enhanced cytotoxicity and antioxidant capacity of kaempferol complexed with α-lactalbumin

M Diao, Y Liang, J Zhao, C Zhao, J Zhang… - Food and Chemical …, 2021 - Elsevier
As a dietary polyphenol, kaempferol exhibits numerous biological activities such as
antioxidant and anticancer properties. However, its application is limited because of its poor …

β-Elemene: mechanistic studies on cancer cell interaction and its chemosensitization effect

Z Jiang, JA Jacob, DS Loganathachetti… - Frontiers in …, 2017 - frontiersin.org
Over the past decade, screening and identifying novel compounds for their biomedical
applications has become an upcoming area of research. Identifying the molecular …

Apigenin-induced apoptosis in A375 and A549 cells through selective action and dysfunction of mitochondria

S Das, J Das, A Samadder… - Experimental …, 2012 - journals.sagepub.com
We isolated apigenin (5, 7, 4'-trihydroxy flavone) from ethanolic extract of Lycopodium
clavatum (LC) used as a homeopathic mother tincture for treatment of various diseases. We …

Hesperetin induces apoptosis in human glioblastoma cells via p38 MAPK activation

Q Li, Z Miao, R Wang, J Yang, D Zhang - Nutrition and Cancer, 2020 - Taylor & Francis
Glioblastoma (GBM) is the most common and aggressive form of malignant brain tumor, with
poor prognosis and a lack of effective treatment. Hesperetin, a natural product found in citrus …

Anticancer effect of tectochrysin in colon cancer cell via suppression of NF-kappaB activity and enhancement of death receptor expression

MH Park, JE Hong, ES Park, HS Yoon, DW Seo… - Molecular cancer, 2015 - Springer
Background Flavonoids are a diverse family of natural phenolic compounds commonly
found in fruits and vegetables. Epidemiologic studies showed that flavonoids also reduce …

Epigallocatechin-3-gallate induces apoptosis in estrogen receptor–negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and …

AM Roy, MS Baliga, SK Katiyar - Molecular cancer therapeutics, 2005 - AACR
Abstract Epigallocatechin-3-gallate (EGCG) has been shown to have anticarcinogenic
effects in in vitro and in vivo models, and this effect is mediated at least in part by its ability to …