[HTML][HTML] Immunosuppressive effect of geniposide on mitogen-activated protein kinase signalling pathway and their cross-talk in fibroblast-like synoviocytes of adjuvant …

F Li, M Dai, H Wu, R Deng, J Fu, Z Zhang, L Dai… - Molecules, 2018 - mdpi.com
Geniposide (GE), an iridoid glycoside compound derived from Gardenia jasminoides Ellis
fruit, is known to have anti-inflammatory and immunoregulatory activities. The aim of this …

Anti-inflammatory effects and pharmacokinetics study of geniposide on rats with adjuvant arthritis

JY Chen, H Wu, H Li, SL Hu, M Dai, J Chen - International …, 2015 - Elsevier
The aim of this study was to explore the anti-inflammatory effects of Geniposide (GE), an
iridoid glycoside compound extracted from Gardenia jasminoides Ellis (GJ) fruit in adjuvant …

Effects and mechanisms of Geniposide on rats with adjuvant arthritis

MM Dai, H Wu, H Li, J Chen, JY Chen, SL Hu… - International …, 2014 - Elsevier
Geniposide (GE), an iridoid glycoside compound, is the major active ingredient of Gardenia
jasminoides Ellis (GJ) fruit which has anti-inflammatory and other important therapeutic …

Immune tolerance effect in mesenteric lymph node lymphocytes of geniposide on adjuvant arthritis rats

ZR Zhang, H Wu, R Wang, SP Li, L Dai… - Phytotherapy …, 2017 - Wiley Online Library
Rheumatoid arthritis (RA) is a systemic, Th1 cytokine‐predominant autoimmune disease
result in a chronic and inflammatory disorder. Geniposide (GE), an iridoid glycoside …

Antiinflammation Effects and Mechanisms Study of Geniposide on Rats with Collagen‐Induced Arthritis

R Wang, H Wu, J Chen, SP Li, L Dai… - Phytotherapy …, 2017 - Wiley Online Library
Geniposide (GE), an iridoid glycoside compound purified from Gardenia jasminoides Ellis,
has antiinflammatory and other pharmacological effects, but its mechanism of actions on …

[HTML][HTML] Anti-inflammatory mechanism of geniposide: inhibiting the hyperpermeability of fibroblast-like synoviocytes via the RhoA/p38MAPK/NF-κB/F-actin signal …

R Deng, F Li, H Wu, W Wang, L Dai… - Frontiers in …, 2018 - frontiersin.org
Geniposide (GE) is the extraction and purification of iridoid glycosides from the Gardenia
jasminoides Ellis, which is a promising anti-inflammatory drug, but its mechanism of actions …

Apoptotic Effect of Geniposide on Fibroblast-Like Synoviocytes in Rats with Adjuvant-Induced Arthritis via Inhibiting ERK Signal Pathway In Vitro

R Li, L Cai, W Tang, C Lei, C Hu, F Yu - Inflammation, 2016 - Springer
Stimulating fibroblast-like synoviocyte (FLS) apoptosis in rheumatoid arthritis (RA) is a
promising strategy for clinical treatment. Previous studies have confirmed that geniposide …

Anti‐inflammatory effect of geniposide on osteoarthritis by suppressing the activation of P38 Mapk Signaling pathway

Y Chen, K Shou, C Gong, H Yang… - BioMed research …, 2018 - Wiley Online Library
It has been suggested that the activation of the p38 mitogen activated protein kinases
(MAPKs) signaling pathway plays a significant role in the progression of OA by leading to …

Penta-acetyl Geniposide suppresses migration, invasion, and inflammation of TNF-α-stimulated rheumatoid arthritis fibroblast-like synoviocytes involving wnt/β …

L Cai, Y Mu, M Liu, M Zhou, B Meng, F Liu, R Li - Inflammation, 2021 - Springer
We previously reported that penta-acetyl geniposide ((Ac) 5GP, an active derivative of
geniposide) showed anti-arthritic effect on adjuvant-induced arthritis (AIA) rats by promoting …

Therapeutic effect of penta-acetyl geniposide on adjuvant-induced arthritis in rats: Involvement of inducing synovial apoptosis and inhibiting NF-κB signal pathway

L Cai, C Li, W Tang, M Liu, W Chen, Y Qiu, R Li - Inflammation, 2018 - Springer
Previous studies demonstrated that penta-acetyl geniposide ((Ac) 5 GP, an acetylated
derivative of geniposide) exhibited better pharmacological functions than geniposide. This …