DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice
ZO Kyjovska, NR Jacobsen, AT Saber… - …, 2015 - academic.oup.com
We investigated the inflammatory response, acute phase response and genotoxic effect of
diesel exhaust particles (DEPs, NIST1650b) following a single intratracheal instillation …
diesel exhaust particles (DEPs, NIST1650b) following a single intratracheal instillation …
Inflammatory and genotoxic effects of diesel particles in vitro and in vivo
M Dybdahl, L Risom, J Bornholdt, H Autrup… - … /Genetic Toxicology and …, 2004 - Elsevier
Recent studies have identified an indirect genotoxicity pathway involving inflammation as
one of the mechanisms underlying the carcinogenic effects of air pollution/diesel exhaust …
one of the mechanisms underlying the carcinogenic effects of air pollution/diesel exhaust …
DNA damage in lung after oral exposure to diesel exhaust particles in Big Blue® rats
AK Müller, EO Farombi, P Møller, HN Autrup… - Mutation Research …, 2004 - Elsevier
Several chemical mutagens and carcinogens, including polycyclic aromatic hydrocarbons
(PAHs) and nitrated PAHs, are adsorbed to the surface of diesel exhaust particles (DEP) …
(PAHs) and nitrated PAHs, are adsorbed to the surface of diesel exhaust particles (DEP) …
Particle characterization and toxicity in C57BL/6 mice following instillation of five different diesel exhaust particles designed to differ in physicochemical properties
Background Diesel exhaust is carcinogenic and exposure to diesel particles cause health
effects. We investigated the toxicity of diesel exhaust particles designed to have varying …
effects. We investigated the toxicity of diesel exhaust particles designed to have varying …
Oxidative damage to DNA by diesel exhaust particle exposure in co-cultures of human lung epithelial cells and macrophages
K Jantzen, M Roursgaard, C Desler, S Loft… - …, 2012 - academic.oup.com
Studies in mono-culture of cells have shown that diesel exhaust particles (DEPs) increase
the production of reactive oxygen species (ROS) and oxidative stress–related damage to …
the production of reactive oxygen species (ROS) and oxidative stress–related damage to …
Micronucleus induction and phagocytosis in mammalian cells treated with diesel emission particles
G Zu-Wei, Z Bao-Zhen, B Nath, W Wen-Zong… - Mutation Research …, 1992 - Elsevier
Micronucleus induction and phagocytosis in V79 and CHO cells treated with diesel emission
particles (DEP) were studied. After separation of the sample into supernatant and sediment …
particles (DEP) were studied. After separation of the sample into supernatant and sediment …
Mutagenicity of diesel exhaust particles mediated by cell–particle interaction in mammalian cells
L Bao, S Chen, L Wu, TK Hei, Y Wu, Z Yu, A Xu - Toxicology, 2007 - Elsevier
Diesel exhaust particle (DEP) has been identified as a class 2A human carcinogen and
closely related to the increased incidence of respiratory allergy, cardiopulmonary morbidity …
closely related to the increased incidence of respiratory allergy, cardiopulmonary morbidity …
DNA damage in rats after a single oral exposure to diesel exhaust particles
PH Danielsen, L Risom, H Wallin, H Autrup… - Mutation Research …, 2008 - Elsevier
The gastrointestinal route of exposure to particulate matter is important because particles
are ingested via contaminated foods and inhaled particles are swallowed when removed …
are ingested via contaminated foods and inhaled particles are swallowed when removed …
Can toxicogenomics provide information on the bioreactivity of diesel exhaust particles?
LJ Reynolds, RJ Richards - Toxicology, 2001 - Elsevier
Epidemiologists have linked increased cardio-respiratory hospital admissions, morbidity and
mortality rates and increases in particulate matter with an aerodynamic diameter less than …
mortality rates and increases in particulate matter with an aerodynamic diameter less than …
Pulmonary inflammation and DNA adducts in rats inhaling diesel exhaust or carbon black
RK Wolff, JA Bond, RF Henderson… - Inhalation …, 1990 - Taylor & Francis
Inhaled diesel exhaust has been shown to be carcinogenic to rats. Two mechanisms have
been suggested: a genotoxic effect of organic compounds associated with the diesel soot …
been suggested: a genotoxic effect of organic compounds associated with the diesel soot …