[PDF][PDF] Efficacy of Erlotinib in patients (PTS) with advanced non-small-cell lung cancer (NSCLC) relative to clinical charesteristics: subset analyses from the trust study

S Allan, L BOSQUEE, A Franke, R Pirker… - American Journal of …, 2008 - orbi.uliege.be
Background: Erlotinib is proven to prolong survival, delay symptom progression and improve
quality of life for pts with advanced NSCLC (Shepherd et al. N Engl J Med 2005; 353: 123 …

Efficacy of erlotinib in patients with advanced Non‐small‐cell Lung Cancer (NSCLC): Analysis of the Australian subpopulation of the TRUST study

M Boyer, K Horwood, N Pavlakis… - Asia‐Pacific Journal …, 2012 - Wiley Online Library
Aims: The efficacy of erlotinib (Tarceva, Roche Products, Dee Why, Australia) has been
demonstrated in patients with advanced non‐small‐cell lung cancer (NSCLC). Tarceva lung …

[HTML][HTML] Phase II randomized trial of erlotinib or vinorelbine in chemonaive, advanced, non-small cell lung cancer patients aged 70 years or older

YM Chen, CM Tsai, WC Fan, JF Shih, SH Liu… - Journal of Thoracic …, 2012 - Elsevier
Introduction: The primary objective of this study was to compare the response rates of
elderly, chemonaive patients with advanced non-small cell lung cancer (NSCLC) treated …

[HTML][HTML] Efficacy and safety of erlotinib in 1242 East/South-East Asian patients with advanced non-small cell lung cancer

T Mok, Y Wu, JS Au, C Zhou, L Zhang, RP Perng… - Journal of Thoracic …, 2010 - Elsevier
Introduction: Erlotinib is an epidermal growth factor receptor tyrosine kinase inhibitor that
significantly increases survival for patients with previously treated advanced non-small cell …

Erlotinib in non-small cell lung cancer (NSCLC): Interim safety analysis of the TRUST study

U Gatzemeier, A Ardizzoni, K Horwood… - Journal of Clinical …, 2007 - ascopubs.org
7645 Background: In patients (pts) with relapsed NSCLC, erlotinib 150 mg/d significantly
prolonged survival, delayed symptom progression, and improved quality of life versus …

Approval summary: erlotinib maintenance therapy of advanced/metastatic non-small cell lung cancer (NSCLC)

MH Cohen, JR Johnson, S Chattopadhyay… - The …, 2010 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to:
Evaluate the relationship between EGFR mutation status and clinical outcomes reported in …

Efficacy vs. effectiveness: erlotinib in previously treated non-small-cell lung cancer

N Sheikh, CR Chambers - Journal of Oncology Pharmacy …, 2013 - journals.sagepub.com
Background: A randomized trial carried out by Shepherd et al. in patients with advanced or
metastatic non-small-cell lung cancer showed statistically significant benefit of erlotinib over …

Erlotinib for metastatic non-small-cell lung cancer: first-, second-or third-line setting–does it matter? A single-institution experience

S Ailawadhi, L Derby, R Natarajan, G Fetterly, M Reid… - Oncology, 2009 - karger.com
Background: Erlotinib is approved as treatment for metastatic non-small-cell lung cancer
(NSCLC), following failure of initial therapy. Studies to define patients that derive maximal …

Benefit of erlotinib in patients with non-small-cell lung cancer is related to smoking status, gender, skin rash and radiological response but not to histology and …

M Faehling, R Eckert, S Kuom, T Kamp, KM Stoiber… - Oncology, 2010 - karger.com
Background: Erlotinib is a standard of treatment for metastatic non-small-cell lung cancer
after failure of initial therapy. Patient selection based on clinical factors is under discussion …

[HTML][HTML] First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 …

SM Lee, I Khan, S Upadhyay, C Lewanski… - The lancet …, 2012 - thelancet.com
Background Many patients with advanced non-small-cell lung cancer (NSCLC) receive only
active supportive care because of poor performance status or presence of several …