Abstract Characterization of the mechanisms underlying various types of muscular dystrophy
has been an outstanding triumph of molecular biology. Increasing clarification of the …

The study of the muscle cell in the muscular dystrophies (MDs) has shown that mutant
proteins result in perturbations of many cellular components. MDs have been associated …

There is no doubt that the study of the muscular dystrophies in recent years has been
exciting and rewarding. It has attracted the attention of many investigators of international …

The muscular dystrophies are a group of neuromuscular disorders associated with muscle
weakness and wasting, which in many forms can lead to loss of ambulation and premature …

Several possible mechanisms causing muscular dystrophy were discussed. Defects in
extracellular molecules have more significant effects resulting mainly in congenital muscular …

The muscular dystrophies are a group of heterogeneous genetic diseases characterized by
progressive degeneration and weakness of skeletal muscle. Since the discovery of the first …

Muscular dystrophies are a genetically heterogeneous group of degenerative muscle
disorders. Nearly 30 genes are known to give rise to various forms of muscular dystrophy …

Muscular dystrophies represent a heterogeneous group of disorders, which have been
largely classified by clinical phenotype. In the last 10 years, identification of novel skeletal …

Current molecular genomic approaches to human genetic disorders have led to an
explosion in the identification of the genes and their encoded proteins responsible for these …

Despite recent advances in molecular genetics, it has proven very difficult to arrive at an
accurate and clinically useful classification of the muscular dystrophies. Much of this difficulty …