Highlights•All major subsets of DCs are critical component of anti-tumor immunity.•DCs in
TME show defects in differentiation, activation and functions.•The presence inf-DCs with anti …

The complexity of the tumor immunoenvironment is underscored by the emergence and
discovery of different subsets of immune effectors and regulatory cells. Tumor-induced …

Dendritic cells (DCs) play a pivotal role in the tumor microenvironment, which is known to
affect disease progression in many human malignancies. Infiltration by mature, active DCs …

Dendritic cells (DCs) are a heterogeneous group of antigen-presenting innate immune cells
that regulate adaptive immunity, including against cancer. Therefore, understanding the …

Among all immune cells, dendritic cells (DC) are the most potent APCs in the immune
system and are central players of the adaptive immune response. There are phenotypically …

Researchers and clinicians have tried for decades to use the mechanisms of immunity for
the fight against cancer. Early attempts aimed at the instrumentation of soluble immune …

Inducing effective anti-tumor immunity has become a major therapeutic strategy against
cancer. Dendritic cells (DC) are a heterogenous population of antigen presenting cells that …

Dendritic cells (DCs) are a diverse group of specialized antigen-presenting cells with key
roles in the initiation and regulation of innate and adaptive immune responses. As such …

Dendritic cells (DC), which consist of several different subsets, specialize in antigen
presentation and are critical for mediating the innate and adaptive immune responses. DC …

Several reports have demonstrated that tumours are not intrinsically resistant to the immune
response. However, neoplasias commonly fail to initiate and maintain adequate immunity. A …