Interactions between the nervous and immune systems were recognized long ago, but
recent studies show that this crosstalk occurs more frequently than was previously …

The nervous system and the immune system are the principal sensory interfaces between
the internal and external environment. They are responsible for recognizing, integrating, and …

It is becoming evident that neurons express an unusual number of molecules that were
originally thought to be specific to immune functions. One such molecule, class I major …

The interaction between the sympathetic nervous system and the immune system has been
documented over the last several decades. In this review, the neuroanatomical, cellular, and …

A conceptual obstacle for understanding immune-to-brain signaling is the issue of the blood–
brain barrier (BBB). In the last 30 years, several pathways have been investigated to …

To define the systemic neuroimmune interactions in health and disease, we recently
suggested immunoception as a term that refers to the existence of bidirectional functional …

Strong evidence is emerging that the nervous and immune systems share mechanisms of
gene regulation, signaling, cell communication, and supracellular organization. This brings …

The central nervous system (CNS) has traditionally been considered to be immunologically
privileged, but over the years there has been a re-evaluation of this dogma. To date, studies …

An important question to ask when preparing an article for immunologists that discusses an
interaction between the brain and the immune system relates to whether an immunologist …

Communication between the central nervous and immune systems lies at the heart of the
neuroimmune axis. We trace here some of the major conceptual hurtles which were raised …