Secondary lymphoid organ chemokines have been implicated in chronic inflammation. Their
expression in the central nervous system (CNS) has not been studied. Here, levels of …

The ELR+ CXC chemokines CXCL1 and CXCL2 are up-regulated in the central nervous
system (CNS) during multiple sclerosis (MS) and its animal model, experimental …

Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease characterized by
leukocyte infiltration into the central nervous system (CNS). Migration of lymphocyte …

Subsequent to demyelination in multiple sclerosis, myelin repair occurs but, as lesions age,
the ability to remyelinate diminishes. Molecular pathways underlying oligodendrocyte …

The chemokine, CXC motif ligand 13 (CXCL13), is constitutively expressed in lymphoid
organs and controls the recruitment and compartmentalization of lymphocytes and antigen …

The chemokines CXCL9 and CXCL10 bind to the common receptor CXCR3 and are
implicated in the pathogenesis of T‐cell‐mediated immunity in the central nervous system …

Multiple Sclerosis (MS) is a chronic inflammatory disease of the CNS which is characterized
by large mononuclear cell infiltration and significant demyelination. CXCL8 is a chemo …

The adoptive transfer of myelin-reactive T cells into wild-type hosts results in spinal cord
inflammation and ascending paralysis, referred to as conventional experimental …

Interleukin 17–producing T helper cells (T H-17 cells) are important in experimental
autoimmune encephalomyelitis, but their route of entry into the central nervous system …

Experimental autoimmune encephalomyelitis (EAE) is a T cell–mediated autoimmune
disease of the central nervous system induced by antigen-specific effector Th17 and Th1 …