The role of peripheral immune cells in the CNS in steady state and disease

M Prinz, J Priller - Nature neuroscience, 2017 - nature.com
The CNS is protected by the immune system, including cells that reside directly within the
CNS and help to ensure proper neural function, as well as cells that traffic into the CNS with …

Natural and induced immunization against CCL20 ameliorate experimental autoimmune encephalitis and may confer protection against multiple sclerosis

M Abraham, A Karni, K Mausner-Fainberg, ID Weiss… - Clinical …, 2017 - Elsevier
Th-17 type immune response that occurs in multiple sclerosis (MS) is linked to CCR6-
CCL20 interaction. We confirmed the dependency on CCR6 in EAE development …

Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell …

JV Kim, N Jiang, CE Tadokoro, L Liu… - Journal of …, 2010 - Elsevier
The mouse spinal cord is an important site for autoimmune and injury models. Skull thinning
surgery provides a minimally invasive window for microscopy of the mouse cerebral cortex …

Expression of CCR7 and CD45RA in CD4+ and CD8+ subsets in cerebrospinal fluid of 134 patients with inflammatory and non-inflammatory neurological diseases

KM Mullen, AR Gocke, R Allie, A Ntranos… - Journal of …, 2012 - Elsevier
We investigated CD45RA and CCR7 expression in CD4+ and CD8+ subsets of
cerebrospinal fluid (CSF) lymphocytes, both immediately ex vivo and after stimulation, from …

[HTML][HTML] Corrigendum: Role of the CXCL13/CXCR5 axis in autoimmune diseases

Z Pan, T Zhu, Y Liu, N Zhang - Frontiers in Immunology, 2022 - frontiersin.org
There were errors in the body text of our original article. In the CXCL13/CXCR5 Protein
Structure section, we unintentionally misinterpreted the cited article by Rosenberg et al …

Sickness behaviour is induced by a peripheral CXC-chemokine also expressed in multiple sclerosis and EAE

SJ Campbell, U Meier, S Mardiguian, Y Jiang… - Brain, behavior, and …, 2010 - Elsevier
Non-CNS chemokine production may contribute to previously unrecognised components of
Multiple Sclerosis (MS) pathology. Here we show that IL-8, a neutrophil chemoattractant, is …

Neuroprotection and remyelination after autoimmune demyelination in mice that inducibly overexpress CXCL1

KM Omari, SE Lutz, L Santambrogio, SA Lira… - The American journal of …, 2009 - Elsevier
In rodents, the chemokine CXCL1 both induces the proliferation and inhibits the migration of
oligodendrocyte precursor cells. We previously reported that in multiple sclerosis, the same …

Targeting monocyte recruitment in CNS autoimmune disease

L Izikson, RS Klein, AD Luster, HL Weiner - Clinical Immunology, 2002 - Elsevier
Monocytes and macrophages play a pathogenic role in a number of autoimmune
inflammatory diseases. Recent studies in experimental autoimmune encephalomyelitis …

Expression of chemokine receptor CXCR3 on cerebrospinal fluid T-cells is related to active MRI lesion appearance in patients with relapsing–remitting multiple …

E Sindern, T Patzold, LM Ossege, A Gisevius… - Journal of …, 2002 - Elsevier
We evaluated CXCR3 expression on T-cells and levels of its ligand CXCL10 in blood and
cerebrospinal fluid (CSF) of 22 patients with relapsing–remitting multiple sclerosis (RR-MS) …

Chemokine regulation of CNS T-cell infiltration in experimental autoimmune encephalomyelitis

LM Hoffman, WJ Karpus - Research in immunology, 1998 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is a CD4+ Thl lymphocyte-mediated,
autoimmune demyelinating disease that is characterized by mononuclear cell infiltration of …