Visceral adipocytes and the metabolic syndrome

A Tchernof - Nutrition reviews, 2007 - academic.oup.com
Recently, the high responsiveness of omental adipocytes to positive lipolytic stimuli has
been clearly demonstrated in women. We conclude that adipose tissue fatty acid release …

Innate immune control of adipose tissue homeostasis

H Kane, L Lynch - Trends in immunology, 2019 - cell.com
Adipose tissue is a critical regulator of systemic metabolism and normal bodily homeostasis.
Recently, the immune system has been implicated in the regulation of adipose tissue …

The molecular control of adipogenesis, with special reference to lymphatic pathology

ED Rosen - Annals of the New York Academy of Sciences, 2002 - Wiley Online Library
Adipogenesis is the process by which mature fat cells are formed from pre‐adipocytes.
Adipogenesis has come under increasing scrutiny not only because the availability of …

Adipocyte biology

P Trayhurn - Clinical Obesity in Adults and Children, 2009 - Wiley Online Library
Adipocytes, the major cell type within adipose tissue, are key endocrine and secretory cells.
Not only do adipocytes store fatty acids as fuel, but they also synthesize and secrete a wide …

The immune cells in adipose tissue

AW Ferrante Jr - Diabetes, Obesity and Metabolism, 2013 - Wiley Online Library
Although the pathological role of the immune system in several metabolic disorders,
including type 1 diabetes mellitus (T1DM) and Addison's disease, has long been recognized …

Adipose tissue macrophages: their role in adipose tissue remodeling

T Suganami, Y Ogawa - Journal of leukocyte biology, 2010 - academic.oup.com
This review summarizes the role of macrophages in adipose tissue remodeling, particularly
focusing on the paracrine loop between adipocytes and macrophages. The adipose tissue …

Adipose tissue inflammation and ectopic lipid accumulation

T Suganami, M Tanaka, Y Ogawa - Endocrine journal, 2012 - jstage.jst.go.jp
Obesity may be viewed as a chronic low-grade inflammatory disease as well as a metabolic
disease. Indeed, unbalanced production of pro-and anti-inflammatory adipocytokines …

[HTML][HTML] Lymphocytes in obesity-related adipose tissue inflammation

A Chatzigeorgiou, KP Karalis, SR Bornstein… - Diabetologia, 2012 - Springer
Inflammation in the white adipose tissue (WAT) is considered a major player in the
development of insulin resistance. The role of macrophages accumulating in the WAT during …

[HTML][HTML] Resident and migratory adipose immune cells control systemic metabolism and thermogenesis

K Man, A Kallies, A Vasanthakumar - Cellular & molecular immunology, 2022 - nature.com
Glucose is a vital source of energy for all mammals. The balance between glucose uptake,
metabolism and storage determines the energy status of an individual, and perturbations in …

The biology of obesity

P Trayhurn - Proceedings of the Nutrition Society, 2005 - cambridge.org
Obesity is a multidisciplinary area, the 'biology'of which encompasses:(1) the fundamental
mechanisms of energy balance and its regulation;(2) the biological basis for the …