Background Base deficit (BD), anion gap (AG), and albumin corrected anion gap (ACAG)
are used by clinicians to assess the presence or absence of hyperlactatemia (HL). We set …

Anion gap, anion gap corrected for serum albumin, and base deficit are often used as
surrogates for measuring serum lactate. None of these surrogates is postulated to predict …

Background: An elevated lactate level reflects impaired tissue oxygenation and is a predictor
of mortality. Studies have shown that the anion gap is inadequate as a screen for …

The presence of acid-base disturbances, especially metabolic acidosis may negatively affect
the outcome of critically ill patients. Lactic acidosis is the most frequent etiology and has …

The aims of this study were to determine whether standard base excess (SBE) is a useful
diagnostic tool for metabolic acidosis, whether metabolic acidosis is clinically relevant in …

Objective: To evaluate the sensitivity, specificity, and predictive values of an elevated anion
gap as an indicator of hyperlactatemia and to assess the contribution of blood lactate to the …

PURPOSE: The aim of this study was to define the nature of metabolic acidosis in patients
with septic shock on admission to intensive care unit (ICU) using Stewart method. We also …

PURPOSE: To characterize the different components of metabolic acidosis in patients with
hyperlactatemia in order to determine the degree to which lactate is responsible for the …

Metabolic acid-base disorders are comnom clinical problems in ICU patients. Arterial blood
gas analysis and anion gap (AG) are important laboratory data in approaching acid-base …

Many critically ill and injured patients, especially those with metabolic acidosis, have
abnormally high levels of unmeasured anions in their blood. At the same time, such patients …