The RNA polymerase II CTD coordinates transcription and RNA processing
The C-terminal domain (CTD) of the RNA polymerase II largest subunit consists of multiple
heptad repeats (consensus Tyr1–Ser2–Pro3–Thr4–Ser5–Pro6–Ser7), varying in number …
heptad repeats (consensus Tyr1–Ser2–Pro3–Thr4–Ser5–Pro6–Ser7), varying in number …
Phosphorylation and functions of the RNA polymerase II CTD
HP Phatnani, AL Greenleaf - Genes & development, 2006 - genesdev.cshlp.org
The C-terminal repeat domain (CTD), an unusual extension appended to the C terminus of
the largest subunit of RNA polymerase II, serves as a flexible binding scaffold for numerous …
the largest subunit of RNA polymerase II, serves as a flexible binding scaffold for numerous …
The RNA polymerase II CTD: the increasing complexity of a low-complexity protein domain
The largest subunit of RNA polymerase II contains a C-terminal domain (CTD) that plays key
roles in coordinating transcription with co-transcriptional events. The heptapeptide repeats …
roles in coordinating transcription with co-transcriptional events. The heptapeptide repeats …
Evolution of the RNA polymerase II C-terminal domain
JW Stiller, BD Hall - … of the National Academy of Sciences, 2002 - National Acad Sciences
In recent years a great deal of biochemical and genetic research has focused on the C-
terminal domain (CTD) of the largest subunit (RPB1) of DNA-dependent RNA polymerase II …
terminal domain (CTD) of the largest subunit (RPB1) of DNA-dependent RNA polymerase II …
Updating the RNA polymerase CTD code: adding gene-specific layers
S Egloff, M Dienstbier, S Murphy - Trends in Genetics, 2012 - cell.com
The carboxyl-terminal domain (CTD) of RNA polymerase (pol) II comprises multiple tandem
repeats with the consensus sequence Tyr 1-Ser 2-Pro 3-Thr 4-Ser 5-Pro 6-Ser 7 that can be …
repeats with the consensus sequence Tyr 1-Ser 2-Pro 3-Thr 4-Ser 5-Pro 6-Ser 7 that can be …
A structural perspective of CTD function
A Meinhart, T Kamenski, S Hoeppner… - Genes & …, 2005 - genesdev.cshlp.org
The C-terminal domain (CTD) of RNA polymerase II (Pol II) integrates nuclear events by
binding proteins involved in mRNA biogenesis. CTD-binding proteins recognize a specific …
binding proteins involved in mRNA biogenesis. CTD-binding proteins recognize a specific …
Cracking the RNA polymerase II CTD code
S Egloff, S Murphy - Trends in genetics, 2008 - cell.com
The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II comprises
multiple tandem conserved heptapeptide repeats, unique to this eukaryotic RNA …
multiple tandem conserved heptapeptide repeats, unique to this eukaryotic RNA …
Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription
M Heidemann, C Hintermair, K Voß, D Eick - Biochimica et Biophysica Acta …, 2013 - Elsevier
The eukaryotic RNA polymerase II (RNAPII) catalyzes the transcription of all protein
encoding genes and is also responsible for the generation of small regulatory RNAs. RNAPII …
encoding genes and is also responsible for the generation of small regulatory RNAs. RNAPII …
RNA polymerase II carboxy-terminal domain kinases: emerging clues to their function
G Prelich - Eukaryotic Cell, 2002 - Am Soc Microbiol
The cloning of the largest subunit of RNA polymerase II (pol II) from mouse and
Saccharomyces cerevisiae in 1985 (3, 28) revealed a remarkable and highly conserved …
Saccharomyces cerevisiae in 1985 (3, 28) revealed a remarkable and highly conserved …
[HTML][HTML] A universal RNA polymerase II CTD cycle is orchestrated by complex interplays between kinase, phosphatase, and isomerase enzymes along genes
Transcription by RNA polymerase II (RNAPII) is coupled to mRNA processing and chromatin
modifications via the C-terminal domain (CTD) of its largest subunit, consisting of multiple …
modifications via the C-terminal domain (CTD) of its largest subunit, consisting of multiple …