Interferon system deficiencies exacerbating severe pandemic virus infections
Pandemics are caused by novel pathogens to which pre-existing antibody immunity is
lacking. Under these circumstances, the body must rely on innate interferon-mediated …
lacking. Under these circumstances, the body must rely on innate interferon-mediated …
Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection
J Schuhenn, TL Meister, D Todt… - Proceedings of the …, 2022 - National Acad Sciences
Type I interferons (IFN-I) exert pleiotropic biological effects during viral infections, balancing
virus control versus immune-mediated pathologies, and have been successfully employed …
virus control versus immune-mediated pathologies, and have been successfully employed …
Molecular mimicry may explain multi-organ damage in COVID-19
F Angileri, S Legare, AM Gammazza… - Autoimmunity …, 2020 - ncbi.nlm.nih.gov
Molecular mimicry has been proposed as a cause of the autoimmune phenomena observed
in COVID-19 [1–4], the syndrome associated with the infection by severe acute respiratory …
in COVID-19 [1–4], the syndrome associated with the infection by severe acute respiratory …