[HTML][HTML] Quantitative prediction of mouse class I MHC peptide binding affinity using support vector machine regression (SVR) models
W Liu, X Meng, Q Xu, DR Flower, T Li - BMC bioinformatics, 2006 - Springer
Background The binding between peptide epitopes and major histocompatibility complex
proteins (MHCs) is an important event in the cellular immune response. Accurate prediction …
proteins (MHCs) is an important event in the cellular immune response. Accurate prediction …
[HTML][HTML] SVRMHC prediction server for MHC-binding peptides
J Wan, W Liu, Q Xu, Y Ren, DR Flower, T Li - BMC bioinformatics, 2006 - Springer
Background The binding between antigenic peptides (epitopes) and the MHC molecule is a
key step in the cellular immune response. Accurate in silico prediction of epitope-MHC …
key step in the cellular immune response. Accurate in silico prediction of epitope-MHC …
Examining the independent binding assumption for binding of peptide epitopes to MHC-I molecules
Motivation: Various methods have been proposed to predict the binding affinities of peptides
to Major Histocompatibility Complex class I (MHC-I) molecules based on experimental …
to Major Histocompatibility Complex class I (MHC-I) molecules based on experimental …
NetMHCcons: a consensus method for the major histocompatibility complex class I predictions
A key role in cell-mediated immunity is dedicated to the major histocompatibility complex
(MHC) molecules that bind peptides for presentation on the cell surface. Several in silico …
(MHC) molecules that bind peptides for presentation on the cell surface. Several in silico …
Automated benchmarking of peptide-MHC class I binding predictions
Motivation: Numerous in silico methods predicting peptide binding to major
histocompatibility complex (MHC) class I molecules have been developed over the last …
histocompatibility complex (MHC) class I molecules have been developed over the last …
[HTML][HTML] Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
J Salomon, DR Flower - BMC bioinformatics, 2006 - Springer
Background Modelling the interaction between potentially antigenic peptides and Major
Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell …
Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell …
Accurate approximation method for prediction of class I MHC affinities for peptides of length 8, 10 and 11 using prediction tools trained on 9mers
Several accurate prediction systems have been developed for prediction of class I major
histocompatibility complex (MHC): peptide binding. Most of these are trained on binding …
histocompatibility complex (MHC): peptide binding. Most of these are trained on binding …
Hidden Markov model-based prediction of antigenic peptides that interact with MHC class II molecules
H Noguchi, R Kato, T Hanai, Y Matsubara… - Journal of bioscience …, 2002 - Elsevier
Elucidating the interaction between major histocompatibility complex (MHC) molecules and
antigenic peptides is fundamental to better understanding of the processes involved in …
antigenic peptides is fundamental to better understanding of the processes involved in …
Coupling in silico and in vitro analysis of peptide-MHC binding: a bioinformatic approach enabling prediction of superbinding peptides and anchorless epitopes
IA Doytchinova, VA Walshe, NA Jones… - The Journal of …, 2004 - journals.aai.org
The ability to define and manipulate the interaction of peptides with MHC molecules has
immense immunological utility, with applications in epitope identification, vaccine design …
immense immunological utility, with applications in epitope identification, vaccine design …
Improved methods for predicting peptide binding affinity to MHC class II molecules
Major histocompatibility complex class II (MHC‐II) molecules are expressed on the surface
of professional antigen‐presenting cells where they display peptides to T helper cells, which …
of professional antigen‐presenting cells where they display peptides to T helper cells, which …