Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1–deficient mice

M Furuse, M Hata, K Furuse, Y Yoshida… - The Journal of cell …, 2002 - rupress.org
The tight junction (TJ) and its adhesion molecules, claudins, are responsible for the barrier
function of simple epithelia, but TJs have not been thought to play an important role in the …

Tight junctions form a barrier in human epidermis

N Kirschner, P Houdek, M Fromm, I Moll… - European journal of cell …, 2010 - Elsevier
Tight junctions (TJ) are cell–cell junctions that have proved to form a paracellular barrier for
solutes and water between cells of epithelia, including the stratum granulosum of the …

Tight junction proteins in keratinocytes: localization and contribution to barrier function

T Yuki, A Haratake, H Koishikawa… - Experimental …, 2007 - Wiley Online Library
Recent research suggests that tight junctions (TJs) are located in the stratum granulosum,
where they contribute to the barrier function of the epidermis. In this study, we investigated …

[HTML][HTML] Tight junction proteins claudin-1 and occludin are important for cutaneous wound healing

T Volksdorf, J Heilmann, SA Eming… - The American journal of …, 2017 - Elsevier
Tight junction (TJ) proteins are known to be involved in proliferation and differentiation.
These processes are essential for normal skin wound healing. Here, we investigated the TJ …

Tight junction dysfunction in the stratum granulosum leads to aberrant stratum corneum barrier function in claudin-1-deficient mice

T Sugawara, N Iwamoto, M Akashi, T Kojima… - Journal of …, 2013 - Elsevier
BACKGROUND: Tight junctions (TJs) contribute to the epithelial barrier function by
preventing leakage of solutes through the intercellular space. In the skin, TJs occur in the …

Tight junction proteins in the skin

JM Brandner, S Kief, E Wladykowski… - Skin pharmacology and …, 2006 - karger.com
It has long been accepted that tight junctions (TJ) are crucial for the formation and
maintenance of the paracellular barrier and for cell polarity in simple epithelia and …

Barriers and more: functions of tight junction proteins in the skin

N Kirschner, JM Brandner - Annals of the New York Academy of …, 2012 - Wiley Online Library
Although the existence of tight junction (TJ) structures (or a secondary epidermal barrier)
was postulated for a long time, the first description of TJ proteins in the epidermis (occludin …

Tight junctions and tight junction proteins in mammalian epidermis

JM Brandner - European Journal of Pharmaceutics and …, 2009 - Elsevier
Tight junctions (TJ) are barrier forming cell–cell junctions that are found in a variety of cell
types and tissues but their existence in mammalian epidermis has been shown only in the …

[HTML][HTML] Characterization of tight junctions and their disruption by UVB in human epidermis and cultured keratinocytes

T Yuki, A Hachiya, A Kusaka, P Sriwiriyanont… - Journal of Investigative …, 2011 - Elsevier
It has not been confirmed whether tight junctions (TJs) function as a paracellular
permeability barrier in adult human skin. To clarify this issue, we performed a TJ …

Tight junctions in the skin

K Morita, Y Miyachi - Journal of dermatological science, 2003 - Elsevier
Tight junctions (= zonulae occludentes, TJs) function as an effective barrier in simple
epithelia. Recent developments in the molecular biology of TJs revealed that TJs also exist …