Sepsis is a life-threatening organ dysfunction syndrome caused by dysregulated host
responses to infection. Not only does sepsis pose a serious hazard to human health, but it …

Sepsis is a leading cause of death worldwide. After initial trials modulating the
hyperinflammatory phase of sepsis failed, generations of researchers have focused on …

Sepsis-induced multiple organ dysfunction arises from the highly complex pathophysiology
encompassing the interplay of inflammation, oxidative stress, endothelial dysfunction …

Sepsis represents the host's systemic inflammatory response to a severe infection. It causes
substantial human morbidity resulting in hundreds of thousands of deaths each year …

Sepsis is a life-threatening condition and a global disease burden. Today, the
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …

Mortality remains very high among septic patients despite the advanced treatments
rendered in intensive care units. The development of septic shock is multifactorial. Tissue …

Sepsis—which is a severe life-threatening infection with organ dysfunction—initiates a
complex interplay of host pro-inflammatory and anti-inflammatory processes. Sepsis can be …

Sepsis is the systematic response to infection. In septic patients who develop severe
disease, excessive inflammation damages the lungs, liver, kidneys, and cardiovascular …

Sepsis is one of the most common reasons for critically ill patients to be admitted to an
intensive care unit and, despite advances in overall medical care, it represents a major …

Sepsis and sepsis-associated multi-organ failure are major challenges for scientists and
clinicians and are a tremendous burden for health-care systems. Despite extensive basic …