Protein dyshomeostasis is the common mechanism of neurodegenerative diseases such as
Alzheimer's disease (AD). Aging is the key risk factor, as the capacity of the proteostasis …

Amyloid-β (Aβ) is a dynamic peptide of Alzheimer's disease (AD) which accelerates the
disease progression. At the cell membrane and cell compartments, the amyloid precursor …

As the population is aging, the incidence of age-related neurodegenerative diseases, such
as Alzheimer and Parkinson disease, is growing. The pathology of neurodegenerative …

Alzheimer's Disease (AD) is a slow-developing neurodegenerative disorder in which the
main pathogenic role has been assigned to β-amyloid protein (Aβ) that accumulates in …

The ubiquitin-proteasomal-system (UPS) and the autophagy-lysosomal-system (ALS) are
both highly susceptible for disturbances leading to the accumulation of cellular damage. A …

Amyloid beta (Aβ) is an intricate molecule that interacts with several biomolecules and/or
produces insoluble assemblies and eventually the nonphysiological depositions of its …

Alzheimer's disease (AD) is one key medical challenge of the aging society and despite a
great amount of effort and a huge collection of acquired data on molecular mechanisms that …

Amyloid-β (Aβ) accumulation is one of the cardinal pathological hallmarks of Alzheimer's
disease and plays an important role in its pathogenesis. Although the neurotoxic effects of …

Alzheimer's disease (AD) and stroke are two interrelated neurodegenerative disorders
which are the leading cause of death and affect the neurons in the brain and central nervous …

Alzheimer's disease (AD) is a central nervous system disease characterized by progressive
cognitive dysfunction and memory loss. Increasing evidences suggest that β amyloid (Aβ) …