Spatiotemporal complexity of the aortic sinus vortex as a function of leaflet calcification

H Hatoum, LP Dasi - Annals of biomedical engineering, 2019 - Springer
Several studies have shown the variation of aortic sinus structures' hemodynamics with
different flow and geometric characteristics. They have also correlated aortic sinus …

Coronary flow impacts aortic leaflet mechanics and aortic sinus hemodynamics

BL Moore, LP Dasi - Annals of biomedical engineering, 2015 - Springer
Mechanical stresses on aortic valve leaflets are well-known mediators for initiating
processes leading to calcific aortic valve disease. Given that non-coronary leaflets calcify …

Sinus hemodynamics in representative stenotic native bicuspid and tricuspid aortic valves: an in-vitro study

H Hatoum, LP Dasi - Fluids, 2018 - mdpi.com
(1) The study's objective is to assess sinus hemodynamics differences between stenotic
native bicuspid aortic valve (BAV) and native tricuspid aortic valve (TrAV) sinuses in order to …

Effect of left and right coronary flow waveforms on aortic sinus hemodynamics and leaflet shear stress: correlation with calcification locations

DC Flemister, H Hatoum, V Guhan, B Zebhi… - Annals of biomedical …, 2020 - Springer
Coronary flow induces hemodynamic alterations in the aortic sinus region. The objectives of
this study are to:(1) investigate the differences among sinus hemodynamics and leaflet wall …

Spatiotemporal complexity of the aortic sinus vortex

B Moore, LP Dasi - Experiments in fluids, 2014 - Springer
The aortic sinus vortex is a classical flow structure of significant importance to aortic valve
dynamics and the initiation and progression of calcific aortic valve disease. We characterize …

Effect of blood pressure levels on sinus hemodynamics in relation to calcification after bioprosthetic aortic valve replacement

B Vogl, A Sularz, S Lilly, VH Thourani… - Annals of biomedical …, 2024 - Springer
Coexisting hypertension and aortic stenosis are common. Some studies showed that
elevated blood pressures may be associated with progression of calcific aortic valve disease …

[HTML][HTML] Impact of patient-specific morphologies on sinus flow stasis in transcatheter aortic valve replacement: an in vitro study

H Hatoum, J Dollery, SM Lilly, J Crestanello… - The Journal of thoracic …, 2019 - Elsevier
Objective The goal of this study is to evaluate how sinus flow patterns after transcatheter
aortic valve replacement in realistic representative patient roots vary. Sinus flow can affect …

Effect of the position of the coronary sinus orifice on aortic leaflet coaptation

Y PAN, A QIAO, N DONG - Journal of Mechanics in Medicine and …, 2014 - World Scientific
Background: The various components of the aortic root maintain a particular geometric
relationship to guarantee unobstructed blood flow across the aortic valve and valve …

Hemodynamics of a stenosed aortic valve: effects of the geometry of the sinuses and the positions of the coronary ostia

AR Kivi, N Sedaghatizadeh, BS Cazzolato… - International Journal of …, 2020 - Elsevier
Aortic valve stenosis is one of the most prevalent cardiovascular disease among adults
worldwide. Stenosis of the aortic valve changes the hemodynamic parameters inside the …

Fluid flow characteristics of healthy and calcified aortic valves using three-dimensional Lagrangian coherent structures analysis

O Mutlu, HE Salman, HC Yalcin, AB Olcay - Fluids, 2021 - mdpi.com
Aortic valve calcification is an important cardiovascular disorder that deteriorates the
accurate functioning of the valve leaflets. The increasing stiffness due to the calcification …