Abstract Flap endonuclease 1 (FEN1) is a structure-specific nuclease best known for its
critical roles in Okazaki fragment maturation, DNA repair, and apoptosis-induced DNA …

Abstract Flap endonuclease-1 (FEN1) is a multifunctional, structure-specific nuclease that
has a critical role in maintaining human genome stability. FEN1 mutations have been …

Flap endonuclease 1 (FEN1) plays a crucial role in both DNA replication and damage
repair. In this study, FEN1 expression and its clinical-pathologic significance in non–small …

FEN1 has key roles in Okazaki fragment maturation during replication, long patch base
excision repair, rescue of stalled replication forks, maintenance of telomere stability and …

Abstract Flap endonuclease 1 (Fen1) is a key enzyme for maintaining genetic stability in
eukaryotic genomes. Haploinsufficiency of Fen1 leads to the rapid progression of tumours in …

As a DNA repair protein, flap endonuclease 1 (FEN1), a structure-specific 5'nuclease, plays
pivotal roles in the maturation of Okazaki fragments, long-patch base excision repair …

DNA replication and repair are critical processes for all living organisms to ensure faithful
duplication and transmission of genetic information. Flap endonuclease 1 (Fen1), a structure …

Abstract DNA flap endonuclease 1 (FEN1) plays critical roles in maintaining genome
stability and integrity by participating in both DNA replication and repair. Suppression of …

Abstract Flap endonuclease 1 (FEN1), a structure-specific endo-and exonuclease, has
multiple functions that determine essential biological processes, such as cell proliferation …

Flap endonuclease 1 (FEN1) is a DNA replication/repair protein involved in Okazaki
fragment processing, long-patch base excision repair, DNA double-strand break repair and …