Comparison of intranasal and transcutaneous immunization for induction of protective immunity against Chlamydia muridarum respiratory tract infection

KA Skelding, DK Hickey, JC Horvat, S Bao, KG Roberts… - Vaccine, 2006 - Elsevier
Chlamydia pneumoniae causes a range of respiratory infections including bronchitis,
pharyngitis and pneumonia. Infection has also been implicated in exacerbation/initiation of …

Immunization with a MOMP-Based Vaccine Protects Mice against a Pulmonary Chlamydia Challenge and Identifies a Disconnection between Infection and Pathology

CP O'Meara, CW Armitage, MCG Harvie, P Timms… - PLoS …, 2013 - journals.plos.org
Chlamydia pneumoniae is responsible for up to 20% of community acquired pneumonia and
can exacerbate chronic inflammatory diseases. As the majority of infections are either mild …

Intranasal Vaccination with Chlamydia pneumoniae Induces Cross-Species Immunity against Genital Chlamydia muridarum Challenge in Mice

S Manam, BKR Chaganty, SJ Evani, MT Zafiratos… - PLoS …, 2013 - journals.plos.org
Chlamydia trachomatis is the most common bacterial sexually transmitted disease in the
world and specifically in the United States, with the highest incidence in age-groups 14–19 …

Immunoprophylaxis of Chlamydia trachomatis lymphogranuloma venereum pneumonitis in mice by oral immunization

ZD Cui, LJ LaScolea Jr, J Fisher, PL Ogra - Infection and immunity, 1989 - Am Soc Microbiol
Groups of BALB/c mice were orally immunized with chlamydiae and challenged intranasally
to determine whether oral immunization offers protection against pulmonary disease and to …

Priming with Chlamydia trachomatis Major Outer Membrane Protein (MOMP) DNA followed by MOMP ISCOM Boosting Enhances Protection and Is Associated with …

Z Dong-Ji, X Yang, C Shen, H Lu, A Murdin… - Infection and …, 2000 - Am Soc Microbiol
We previously reported that DNA vaccination was able to elicit cellular immune responses
and partial protection against Chlamydia trachomatis infection. However, DNA immunization …

Vaccination with the Chlamydia trachomatis Major Outer Membrane Protein Can Elicit an Immune Response as Protective as That Resulting from Inoculation with …

S Pal, EM Peterson, LM de la Maza - Infection and immunity, 2005 - Am Soc Microbiol
ABSTRACT BALB/c mice were vaccinated by the intramuscular (im) and subcutaneous (sc)
routes with a native preparation of the Chlamydia trachomatis mouse pneumonitis (MoPn) …

Enhancement of the protective efficacy of a Chlamydia trachomatis recombinant vaccine by combining systemic and mucosal routes for immunization

P Ralli-Jain, D Tifrea, C Cheng, S Pal, LM De la Maza - Vaccine, 2010 - Elsevier
Chlamydia trachomatis causes respiratory and sexually transmitted infections. Here, we
tested a vaccine formulated with the recombinant major outer membrane protein from C …

Protection of wild-type and severe combined immunodeficiency mice against an intranasal challenge by passive immunization with monoclonal antibodies to the …

S Pal, J Bravo, EM Peterson… - Infection and …, 2008 - Am Soc Microbiol
Monoclonal antibodies (MAbs) to the Chlamydia trachomatis mouse pneumonitis (MoPn)
major outer membrane protein (MOMP) were characterized for their ability to neutralize the …

Immunization with the Chlamydia trachomatis Mouse Pneumonitis Major Outer Membrane Protein by Use of CpG Oligodeoxynucleotides as an Adjuvant Induces a …

S Pal, HL Davis, EM Peterson… - Infection and …, 2002 - Am Soc Microbiol
Recently, we have shown that a vaccine consisting of a purified preparation of the
Chlamydia trachomatis mouse pneumonitis (MoPn) major outer membrane protein (MOMP) …

Use of a Mouse Lung Challenge Model to Identify Antigens Protective against Chlamydia pneumoniae Lung Infection

AD Murdin, P Dunn, R Sodoyer, J Wang… - The Journal of …, 2000 - academic.oup.com
Chlamydia pneumoniae is emerging as a significant human pathogen. Infection causes a
range of respiratory tract diseases and is associated with atherosclerosis. A vaccine could …