Assessment of T-cell reactivity to the SARS-CoV-2 omicron variant by immunized individuals

L De Marco, S D'Orso, M Pirronello… - JAMA network …, 2022 - jamanetwork.com
Importance The emergence of the highly contagious Omicron variant of SARS-CoV-2 and
the findings of a significantly reduced neutralizing potency of sera from individuals with …

[HTML][HTML] SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection

S Cele, L Jackson, DS Khoury, K Khan, T Moyo-Gwete… - MedRxiv, 2021 - ncbi.nlm.nih.gov
The emergence of SARS-CoV-2 Omicron, first identified in Botswana and South Africa, may
compromise vaccine effectiveness and the ability of antibodies triggered by previous …

SARS-CoV-2 spike T cell responses induced upon vaccination or infection remain robust against Omicron

R Keeton, MB Tincho, A Ngomti, R Baguma, N Benede… - MedRxiv, 2021 - medrxiv.org
Summary The SARS-CoV-2 Omicron variant has multiple Spike (S) protein mutations that
contribute to escape from the neutralizing antibody responses, and reducing vaccine …

[PDF][PDF] Rapid emergence of SARS-CoV-2 Omicron variant is associated with an infection advantage over Delta in vaccinated persons

C Chaguza, A Coppi, R Earnest, D Ferguson… - Med, 2022 - cell.com
Summary Background The SARS-CoV-2 Omicron variant became a global concern due to
its rapid spread and displacement of the dominant Delta variant. We hypothesized that part …

[PDF][PDF] mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant

WF Garcia-Beltran, KJS Denis, A Hoelzemer, EC Lam… - Cell, 2022 - cell.com
Recent surveillance has revealed the emergence of the SARS-CoV-2 Omicron variant (BA.
1/B. 1.1. 529) harboring up to 36 mutations in spike protein, the target of neutralizing …

[PDF][PDF] The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the endosomal route of entry

TP Peacock, JC Brown, J Zhou, N Thakur… - …, 2022 - pdfs.semanticscholar.org
At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread
across the world. It has been demonstrated that Omicron's high number of Spike mutations …

Imprinted antibody responses against SARS-CoV-2 Omicron sublineages

YJ Park, D Pinto, AC Walls, Z Liu, A De Marco… - Science, 2022 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry
distinct spike mutations resulting in escape from antibodies induced by previous infection or …

SARS‐CoV‐2 Omicron variant: Immune escape and vaccine development

D Ao, T Lan, X He, J Liu, L Chen, DT Baptista‐Hon… - MedComm, 2022 - Wiley Online Library
New genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
constantly emerge through unmitigated spread of the virus in the ongoing Coronavirus …

[HTML][HTML] Molecular basis of receptor binding and antibody neutralization of Omicron

Q Hong, W Han, J Li, S Xu, Y Wang, C Xu, Z Li, Y Wang… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant exhibits striking immune evasion and is
spreading rapidly worldwide. Understanding the structural basis of the high transmissibility …

Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters

S Yuan, ZW Ye, R Liang, K Tang, AJ Zhang, G Lu… - Science, 2022 - science.org
The in vivo pathogenicity, transmissibility, and fitness of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) Omicron (B. 1.1. 529) variant are not well …