A combination of unusual transcription factors binds cooperatively to control Myxococcus xanthus developmental gene expression

S Mittal, L Kroos - Proceedings of the National Academy of …, 2009 - National Acad Sciences
Myxococcus xanthus is a bacterium that undergoes multicellular development requiring
coordinate regulation of multiple signaling pathways. One pathway governs aggregation …

Combinatorial Regulation by a Novel Arrangement of FruA and MrpC2 Transcription Factors during Myxococcus xanthus Development

S Mittal, L Kroos - Journal of bacteriology, 2009 - Am Soc Microbiol
Myxococcus xanthus is a gram-negative soil bacterium that undergoes multicellular
development upon nutrient limitation. Intercellular signals control cell movements and …

Myxococcus xanthus developmental cell fate production: heterogeneous accumulation of developmental regulatory proteins and reexamination of the role of MazF in …

B Lee, C Holkenbrink, A Treuner-Lange… - Journal of …, 2012 - Am Soc Microbiol
Myxococcus xanthus undergoes a starvation-induced multicellular developmental program
during which cells partition into three known fates:(i) aggregation into fruiting bodies …

Combinatorial Regulation of fmgD by MrpC2 and FruA during Myxococcus xanthus Development

J Lee, B Son, P Viswanathan, PM Luethy… - Journal of …, 2011 - Am Soc Microbiol
Upon starvation, a dense population of rod-shaped Myxococcus xanthus bacteria coordinate
their movements to construct mounds in which some of the cells differentiate to spherical …

Transcription factor MrpC binds to promoter regions of hundreds of developmentally-regulated genes in Myxococcus xanthus

M Robinson, B Son, D Kroos, L Kroos - BMC genomics, 2014 - Springer
Background Myxococcus xanthus is a bacterium that undergoes multicellular development
when starved. Cells move to aggregation centers and form fruiting bodies in which cells …

MrpC, a CRP/Fnr homolog, functions as a negative autoregulator during the Myxococcus xanthus multicellular developmental program

M McLaughlin, V Bhardwaj, BE Feeley… - Molecular …, 2018 - Wiley Online Library
MrpC, a member of the CRP/Fnr superfamily of transcriptional regulators, plays a key role in
coordination of the multicellular developmental program in Myxococcus xanthus. Previous …

Combinatorial Regulation by MrpC2 and FruA Involves Three Sites in the fmgE Promoter Region during Myxococcus xanthus Development

B Son, Y Liu, L Kroos - Journal of bacteriology, 2011 - Am Soc Microbiol
Starvation causes cells in a dense population of Myxococcus xanthus to change their gliding
movements and construct mounds. Short-range C-signaling between rod-shaped cells …

A protein Ser/Thr kinase cascade negatively regulates the DNA‐binding activity of MrpC, a smaller form of which may be necessary for the Myxococcus xanthus …

H Nariya, S Inouye - Molecular microbiology, 2006 - Wiley Online Library
The developmental process of Myxococcus xanthus is achieved by the expression of a
specific set of genes under the influence of developmental signals. MrpC is a member of the …

MazF, an mRNA interferase, mediates programmed cell death during multicellular Myxococcus development

H Nariya, M Inouye - Cell, 2008 - cell.com
In prokaryotes, the toxin-antitoxin systems are thought to play important roles in growth
regulation under stress conditions. In the E. coli MazE-MazF system, MazF toxin functions as …

Molecular mechanisms of signaling in Myxococcus xanthus development

DJ Bretl, JR Kirby - Journal of molecular biology, 2016 - Elsevier
Myxococcus xanthus is an environmental bacterium that displays a complex life cycle that
includes motility, predation, multicellular fruiting body development, and sporulation. Given …