Topical application of photofrin for photodynamic diagnosis of oral neoplasms

CJ Chang, P Wilder-Smith - Plastic and reconstructive surgery, 2005 - journals.lww.com
Background: The prognosis of patients with oral cancer can be improved by early diagnosis.
Exact demarcation of tumor margins could contribute to optimum results in surgical excision …

Autofluorescence and Photofrin-induced fluorescence imaging and spectroscopy in an animal model of oral cancer

T Mang, J Kost, M Sullivan, BC Wilson - Photodiagnosis and Photodynamic …, 2006 - Elsevier
Developments in the fluorescence detection of cancer aim either to distinguish tissue
autofluorescence from that of injected fluorophores or to exploit differences in …

[HTML][HTML] Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy

A Sharwani, W Jerjes, V Salih, AJ MacRobert… - … of Photochemistry and …, 2006 - Elsevier
BACKGROUND: Early detection of premalignant/malignant lesions in the oral cavity can
certainly improve the patient's prognosis. This study presents fluorescence imaging with the …

Treatment outcome of Photofrin-based photodynamic therapy for T1 and T2 oral squamous cell carcinoma and dysplasia

H Ikeda, T Tobita, S Ohba, M Uehara… - … and photodynamic therapy, 2013 - Elsevier
Background Photodynamic therapy (PDT) is a minimally invasive treatment modality for
early and superficial malignancy or premalignancy in the head and neck regions. However …

Clinical pharmacokinetic studies of photofrin by fluorescence spectroscopy in the oral cavity, the esophagus, and the bronchi

DR Braichotte, GA Wagnières, R Bays, P Monnier… - Cancer, 1995 - Wiley Online Library
Background. To optimize photodynamic therapy (PDT) and photodetection of cancer, two
important variables that must be considered are the uptake of the dye and the dye contrast …

In vivo photo-detection of chemically induced premalignant lesions and squamous cell carcinoma of the rat palatal mucosa

JM Nauta, OC Speelman, H Van Leengoed… - … of Photochemistry and …, 1997 - Elsevier
Photo-detection using in vivo fluorescence was studied for different stages of chemically
induced premalignant lesions and squamous cell carcinoma (SCC) of the Wistar rat palatal …

Detection of squamous neoplasia by fluorescence imaging comparing porfimer sodium fluorescence to tissue autofluorescence in the hamster cheek-pouch model

I Pathak, NL Davis, YN Hsiang, NF Quenville… - The American journal of …, 1995 - Elsevier
Background: Early neoplastic changes in the oral cavity may be difficult to detect.
Fluorescence imaging using porphyrin-derived drugs has been used to enhance detection …

Photodynamic diagnosis of neoplasms of the mouth cavity after local administration of 5-aminolevulinic acid

A Leunig, K Rick, H Stepp, A Goetz… - Laryngo-Rhino …, 1996 - europepmc.org
Background The aim of photodynamic diagnosis (PDD) is the complete visualization of all
neoplastic lesions in a tumorous organ after topical or systemic application of a tumor …

A comparative study of normal inspection, autofluorescence and 5‐ALA‐induced PPIX fluorescence for oral cancer diagnosis

CS Betz, H Stepp, P Janda, S Arbogast… - … journal of cancer, 2002 - Wiley Online Library
Fluorescence diagnosis aims to improve the management of oral cancer via early detection
of the malignant lesions and better delimitation of the tumor margins. This paper presents a …

Porphyrinoids in photodynamic diagnosis and therapy of oral diseases

A Glowacka-Sobotta, M Wrotynski… - Journal of Porphyrins …, 2019 - World Scientific
Photodynamic methods have found application not only in the treatment process as
photodynamic therapy but also for the early detection of neoplastic lesions and tumors as …