Abstract 'If G-quadruplexes form so readily in vitro, Nature will have found a way of using
them in vivo'(Statement by Aaron Klug over 30 years ago). During the last decade, four …

Cell-cycle-synchronized DNA replication and cellular-environment-dependent gene
expression are mainly controlled by proteins and DNAs with higher-order structures, such as …

The research on the G-quadruplex DNAs has received much attention in recent years and
numerous reports appeared probing their detection, structure, stability, reactivity, selectivity …

The proximal promoter region of many human growth-related genes contains a polypurine/
polypyrimidine tract that serves as multiple binding sites for Sp1 or other transcription …

G-quadruplex structures are among the most interesting and best-characterized DNA folding
motifs.[1] DNA sequences that can form stable G-quadruplexes in vitro have been implicated …

The secondary structures of nucleic acids have an important influence on their cellular
functions but can be difficult to identify and classify quickly. Here, we show that an arrayed …

G-Quadruplexes (G4s) are four-stranded nucleic acid structures whose underlying G-rich
sequences are present across the chromosome and transcriptome. These highly structured …

Four-stranded DNA structures formed by guanine-rich sequences are known as G-
quadruplexes. They have received much interest over the last decade owing to their …

A tailor-made colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic
acids was developed by incorporating a coumarin–hemicyanine fluorophore into an …

The intriguing structural diversity in folded topologies available to guanine-rich nucleic acid
repeat sequences have made four-stranded G-quadruplex structures the focus of both basic …