Discovery of new cellulases from the metagenome by a metagenomics-guided strategy

C Yang, Y Xia, H Qu, AD Li, R Liu, Y Wang… - Biotechnology for …, 2016 - Springer
Background Energy shortage has become a global problem. Production of biofuels from
renewable biomass resources is an inevitable trend of sustainable development. Cellulose …

Mining metagenomes for novel cellulase genes

CJ Duan, JX Feng - Biotechnology letters, 2010 - Springer
Abstract Cellulases hydrolyze the β-1, 4 linkages of cellulose and are widely used in food,
brewing and wine, animal feed, textiles and laundry, and pulp and paper industries …

Bioprospecting of functional cellulases from metagenome for second generation biofuel production: a review

R Tiwari, L Nain, NE Labrou… - Critical reviews in …, 2018 - Taylor & Francis
Second generation biofuel production has been appeared as a sustainable and alternative
energy option. The ultimate aim is the development of an industrially feasible and economic …

Discovery of (hemi-) cellulase genes in a metagenomic library from a biogas digester using 454 pyrosequencing

X Yan, A Geng, J Zhang, Y Wei, L Zhang… - Applied Microbiology …, 2013 - Springer
Abstract In this study, 341, 246, and 386 positive clones with endo-β-1, 4-glucanase, β-
glucosidase, and endo-β-1, 4-xylanase activities, respectively, were identified by screening …

Characterization of a metagenome-derived halotolerant cellulase

S Voget, HL Steele, WR Streit - Journal of biotechnology, 2006 - Elsevier
Metagenomes of uncultured microorganisms represent a sheer unlimited resource for
discovery of novel biocatalysts. Here, we report on the biochemical characterisation of a …

Enhanced crystalline cellulose degradation by a novel metagenome-derived cellulase enzyme

F Kholousi Adab, M Mehdi Yaghoobi, J Gharechahi - Scientific Reports, 2024 - nature.com
Metagenomics has revolutionized access to genomic information of microorganisms
inhabiting the gut of herbivorous animals, circumventing the need for their isolation and …

Biochemical and structural characterization of a novel halotolerant cellulase from soil metagenome

R Garg, R Srivastava, V Brahma, L Verma… - Scientific reports, 2016 - nature.com
Cellulase catalyzes the hydrolysis of β-1, 4-linkages of cellulose to produce industrially
relevant monomeric subunits. Cellulases find their applications in pulp and paper, laundry …

Role of metagenomics in prospecting novel endoglucanases, accentuating functional metagenomics approach in second-generation biofuel production: a review

NPP Pabbathi, A Velidandi, T Tavarna, S Gupta… - Biomass Conversion …, 2021 - Springer
As the fossil fuel reserves are depleting rapidly, there is a need for alternate fuels to meet the
day to day mounting energy demands. As fossil fuel started depleting, a quest for alternate …

Functional metagenomic technologies for the discovery of novel enzymes for biomass degradation and biofuel production

H Wang, DJ Hart, Y An - BioEnergy Research, 2019 - Springer
As a long-term solution to fossil fuel depletion, deployment of renewable biofuel from plant
biomass degradation would provide significant economic benefits and energy security …

Discovery and characterization of a thermostable and highly halotolerant GH5 cellulase from an icelandic hot spring isolate

D Zarafeta, D Kissas, C Sayer, SR Gudbergsdottir… - PLoS …, 2016 - journals.plos.org
With the ultimate goal of identifying robust cellulases for industrial biocatalytic conversions,
we have isolated and characterized a new thermostable and very halotolerant GH5 …