A pathogenic non-coding RNA induces changes in dynamic DNA methylation of ribosomal RNA genes in host plants

G Martinez, M Castellano, M Tortosa… - Nucleic acids …, 2014 - academic.oup.com
Viroids are plant-pathogenic non-coding RNAs able to interfere with as yet poorly known
host-regulatory pathways and to cause alterations recognized as diseases. The way in …

Alterations in host DNA methylation in response to constitutive expression of Hop stunt viroid RNA in Nicotiana benthamiana plants

M Castellano, G Martinez, V Pallás, G Gómez - Plant pathology, 2015 - Wiley Online Library
Increasing evidence points to the epigenetic regulation of transcriptional activity as a
general mechanism controlling host response to pathogen infection. Recent results revealed …

Analysis and application of viroid-specific small RNAs generated by viroid-inducing RNA silencing

CR Adkar-Purushothama, Z Zhang, S Li… - Plant Virology Protocols …, 2015 - Springer
Viroids are noncoding RNA pathogens inducing severe to mild disease symptoms on
agriculturally important crop plants. Viroid replication is entirely dependent on host …

Interplay between viroid-induced pathogenesis and RNA silencing pathways

G Gomez, G Martínez, V Pallas - Trends in plant science, 2009 - cell.com
Of all known plant pathogens, viroids have the lowest biological complexity. Their genome
consists of a naked RNA without protein-encoding capacity. However, viroids contain …

Viroid-Induced Symptoms in Nicotiana benthamiana Plants Are Dependent on RDR6 Activity

G Gómez, G Martinez, V Pallás - Plant Physiology, 2008 - academic.oup.com
Viroids are small self-replicating RNAs that infect plants. How these noncoding pathogenic
RNAs interact with hosts to induce disease symptoms is a long-standing unanswered …

Viroid-specific small RNA in plant disease

C Hammann, G Steger - RNA biology, 2012 - Taylor & Francis
Viroids are the smallest autonomous infectious nucleic acids known today. They are non-
coding, unencapsidated, circular RNAs with sizes ranging from 250 to 400 nucleotides and …

[HTML][HTML] Role of RNA silencing in plant-viroid interactions and in viroid pathogenesis

F Di Serio, RA Owens, B Navarro, P Serra… - Virus research, 2023 - Elsevier
Viroids are small, single-stranded, non-protein coding and circular RNAs able to infect host
plants in the absence of any helper virus. They may elicit symptoms in their hosts, but the …

High‐throughput sequencing of Hop stunt viroid‐derived small RNAs from cucumber leaves and phloem

G Martinez, L Donaire, C Llave, V Pallas… - Molecular Plant …, 2010 - Wiley Online Library
Small RNA (sRNA)‐guided processes, referred to as RNA silencing, regulate endogenous
and exogenous gene expression. In plants and some animals, these processes are noncell …

Viroid pathogenesis: A critical appraisal of the role of RNA silencing in triggering the initial molecular lesion

R Flores, B Navarro, S Delgado, P Serra… - FEMS Microbiology …, 2020 - academic.oup.com
The initial molecular lesions through which viroids, satellite RNAs and viruses trigger signal
cascades resulting in plant diseases are hotly debated. Since viroids are circular non …

Viroids: how to infect a host and cause disease without encoding proteins

B Navarro, A Gisel, ME Rodio, S Delgado, R Flores… - Biochimie, 2012 - Elsevier
Despite being composed by a single-stranded, circular, non-protein-coding RNA of just 246–
401 nucleotides (nt), viroids can incite in their host plants symptoms similar to those caused …