Imaging the aqueous humor outflow pathway in human eyes by three-dimensional micro-computed tomography (3D micro-CT)

CR Hann, MD Bentley, A Vercnocke, EL Ritman… - Experimental eye …, 2011 - Elsevier
The site of outflow resistance leading to elevated intraocular pressure in primary open-angle
glaucoma is believed to be located in the region of Schlemm's canal inner wall endothelium …

Visualization of the conventional outflow pathway in the living human eye

L Kagemann, G Wollstein, H Ishikawa, Z Nadler… - Ophthalmology, 2012 - Elsevier
PURPOSE: We sought to visualize the aqueous outflow system in 3 dimensions (3D) in
living human eyes, and to investigate the use of commercially available spectral-domain …

Colocalization of outflow segmentation and pores along the inner wall of Schlemm's canal

ST Braakman, AT Read, DWH Chan, CR Ethier… - Experimental eye …, 2015 - Elsevier
All aqueous humor draining through the conventional outflow pathway must cross the
endothelium of Schlemm's canal (SC), likely by passing through micron-sized …

3D visualization of aqueous humor outflow structures in-situ in humans

L Kagemann, G Wollstein, H Ishikawa, IA Sigal… - Experimental eye …, 2011 - Elsevier
Aqueous humor (AH) exiting the eye via the trabecular meshwork and Schlemm's canal (SC)
passes through the deep and intrascleral venous plexus (ISVP) or directly through aqueous …

Variations in active outflow along the trabecular outflow pathway

EDK Cha, J Xu, L Gong, H Gong - Experimental eye research, 2016 - Elsevier
Previous tracer studies have shown segmental outflow in the trabecular meshwork (TM) and
along the inner wall (IW) of Schlemm's canal (SC). Whether segmental outflow is conserved …

[HTML][HTML] Aqueous outflow regulation: Optical coherence tomography implicates pressure-dependent tissue motion

C Xin, RK Wang, S Song, T Shen, J Wen… - Experimental eye …, 2017 - Elsevier
Glaucoma is a leading cause of blindness worldwide and results from damage to the optic
nerve. Currently, intraocular pressure is the only treatable risk factor. Changes in aqueous …

Morphometric analysis of aqueous humor outflow structures with spectral-domain optical coherence tomography

AW Francis, L Kagemann, G Wollstein… - … & visual science, 2012 - iovs.arvojournals.org
PURPOSE. To describe morphometric details of the human aqueous humor (AH) outflow
microvasculature visualized with 360-degree virtual castings during active AH outflow in …

[HTML][HTML] Preferential fluid flow in the human trabecular meshwork near collector channels

CR Hann, MP Fautsch - Investigative ophthalmology & visual …, 2009 - arvojournals.org
purpose. To determine whether preferential pathways exist within the human trabecular
meshwork, pigmented and nonpigmented regions adjacent to and between collector …

Three‐dimensional reconstruction of aqueous channels in human trabecular meshwork using light microscopy and confocal microscopy

JJ Camp, CR Hann, DH Johnson, JE Tarara… - …, 1997 - Wiley Online Library
Conventional two‐dimensional imaging of the trabecular meshwork (TM) provides limited
information about the size, shape, and interconnection of the aqueous channels within the …

Characteristics and variations of in vivo Schlemm's canal and collector channel microstructures in enhanced-depth imaging optical coherence tomography

P Li, A Butt, JL Chien, MP Ghassibi… - British Journal of …, 2017 - bjo.bmj.com
Background/aims To characterise in vivo Schlemm's canal (SC) and collector channels (CC)
microstructures using enhanced-depth imaging (EDI) optical coherence tomography (OCT) …