Country-wide assessment of the genetic polymorphism in Plasmodium falciparum and Plasmodium vivax antigens detected with rapid diagnostic tests for malaria

N Mariette, C Barnadas, C Bouchier, M Tichit… - Malaria journal, 2008 - Springer
Abstract Background Rapid diagnostic tests (RDTs) are becoming increasingly
indispensable in malaria management, as a means of increasing the accuracy of diagnosis …

Evaluation of the intra- and inter-specific genetic variability of Plasmodium lactate dehydrogenase

AM Talman, L Duval, E Legrand, V Hubert, S Yen… - Malaria journal, 2007 - Springer
Background Malaria diagnosis is vital to efficient control programmes and the recent advent
of malaria rapid diagnostic tests (RDTs) provides a reliable and simple diagnostic method …

Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests

J Baker, MF Ho, A Pelecanos, M Gatton, N Chen… - Malaria journal, 2010 - Springer
Background Accurate diagnosis is essential for prompt and appropriate treatment of malaria.
While rapid diagnostic tests (RDTs) offer great potential to improve malaria diagnosis, the …

Investigation of Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions and performance of a rapid diagnostic test for identifying asymptomatic malaria infection in …

CM Leonard, A Assefa, JN McCaffery, C Herman… - Malaria Journal, 2022 - Springer
Abstract Background Rapid diagnostic tests (RDTs) are widely used for malaria diagnosis of
both symptomatic and asymptomatic infections. Although RDTs are a reliable and practical …

[HTML][HTML] Insights into the performance of SD Bioline Malaria Ag Pf/Pan rapid diagnostic test and Plasmodium falciparum histidine-rich protein 2 gene variation in …

N Willie, RK Mehlotra, RE Howes… - The American journal …, 2018 - ncbi.nlm.nih.gov
Plasmodium falciparum histidine-rich protein 2 (PfHRP2) forms the basis of many current
malaria rapid diagnostic tests (RDTs). However, the parasites lacking part or all of the pfhrp2 …

Genetic variation in histidine rich proteins among Indian Plasmodium falciparum population: possible cause of variable sensitivity of malaria rapid diagnostic tests

N Kumar, JPN Singh, V Pande, N Mishra, B Srivastava… - Malaria journal, 2012 - Springer
Abstract Background Rapid diagnostic tests (RDTs) have revolutionized the diagnosis of
malaria. Among the various factors affecting RDTs sensitivity is genetic variation of the …

Assessing performance of HRP2 antigen detection for malaria diagnosis in Mozambique

MM Plucinski, B Candrinho, M Dimene… - Journal of clinical …, 2019 - Am Soc Microbiol
Rapid diagnostic tests (RDTs) that detect the Plasmodium falciparum-specific histidine-rich
protein 2 (PfHRP2) antigen are the primary methods for malaria diagnosis in Mozambique …

False-negative malaria rapid diagnostic tests in Rwanda: impact of Plasmodium falciparum isolates lacking hrp2 and declining malaria transmission

CT Kozycki, N Umulisa, S Rulisa, EI Mwikarago… - Malaria journal, 2017 - Springer
Abstract Background Rapid diagnostic tests (RDTs) for histidine rich protein 2 (HRP2) are
often used to determine whether persons with fever should be treated with anti-malarials …

Field performance of ultrasensitive and conventional malaria rapid diagnostic tests in southern Mozambique

B Galatas, A Mayor, H Gupta, N Balanza, IK Jang… - Malaria journal, 2020 - Springer
Background An ultrasensitive malaria rapid diagnostic test (RDT) was recently developed for
the improved detection of low-density Plasmodium falciparum infections. This study aimed to …

Pan-Plasmodium band sensitivity for Plasmodium falciparum detection in combination malaria rapid diagnostic tests and implications for clinical management

ML Gatton, RR Rees-Channer, J Glenn, JW Barnwell… - Malaria journal, 2015 - Springer
Background Malaria rapid diagnostic tests (RDTs) are appropriate for case management,
but persistent antigenaemia is a concern for HRP2-detecting RDTs in endemic areas. It has …