Evaluation of oxidative stress biomarkers in idiopathic pulmonary fibrosis and therapeutic applications: a systematic review
Introduction Idiopathic pulmonary fibrosis (IPF), a fatal lung disease of unknown origin, is
characterized by chronic and progressive fibrosing interstitial pneumonia which …
characterized by chronic and progressive fibrosing interstitial pneumonia which …
[HTML][HTML] Transcriptomic and network analysis identifies shared and unique pathways and immune changes across fibrotic interstitial lung diseases
W Liu, K Huang, XZ Yang, P Wang - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Background: Interstitial lung disease (ILD) encompasses a diverse group of disorders
characterized by chronic inflammation and fibrosis of the pulmonary interstitium. Three ILDs …
characterized by chronic inflammation and fibrosis of the pulmonary interstitium. Three ILDs …
Anoikis and SPP1 in idiopathic pulmonary fibrosis: integrating bioinformatics, cell, and animal studies to explore prognostic biomarkers and PI3K/AKT Signaling …
Y Liao, Y Yang, G Zhou, L Chen, Y Yang… - Expert Review of …, 2024 - Taylor & Francis
Objective This study aims to explore the relevance of anoikis in idiopathic pulmonary fibrosis
(IPF) and identify associated biomarkers and signaling pathways. Method Unsupervised …
(IPF) and identify associated biomarkers and signaling pathways. Method Unsupervised …
Identification of common signatures in idiopathic pulmonary fibrosis and lung cancer using gene expression modeling
D Leng, J Yi, M Xiang, H Zhao, Y Zhang - BMC cancer, 2020 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is associated with an increased risk for lung
cancer, but the underlying mechanisms driving malignant transformation remain largely …
cancer, but the underlying mechanisms driving malignant transformation remain largely …
Shared biomarkers and mechanisms in idiopathic pulmonary fibrosis and non-small cell lung cancer
X Ding, H Liu, Q Xu, T Ji, R Chen, Z Liu, J Dai - International …, 2024 - Elsevier
Background Epidemiological evidence has indicated the occurrence of idiopathic pulmonary
fibrosis (IPF) with coexisting lung cancer is not a coincidence. The pathogenic mechanisms …
fibrosis (IPF) with coexisting lung cancer is not a coincidence. The pathogenic mechanisms …
Identification of diagnostic hub genes related to neutrophils and infiltrating immune cell alterations in idiopathic pulmonary fibrosis
Y Lin, X Lai, S Huang, L Pu, Q Zeng, Z Wang… - Frontiers in …, 2023 - frontiersin.org
Background There is still a lack of specific indicators to diagnose idiopathic pulmonary
fibrosis (IPF). And the role of immune responses in IPF is elusive. In this study, we aimed to …
fibrosis (IPF). And the role of immune responses in IPF is elusive. In this study, we aimed to …
Integrated plasma proteomics and lung transcriptomics reveal novel biomarkers in idiopathic pulmonary fibrosis
P Sivakumar, R Ammar, JR Thompson, Y Luo… - Respiratory …, 2021 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease with a significant
unmet medical need. Development of transformational therapies for IPF is challenging in …
unmet medical need. Development of transformational therapies for IPF is challenging in …
[HTML][HTML] A prognostic model based on clusters of molecules related to epithelial–mesenchymal transition for idiopathic pulmonary fibrosis
J Zhao, C Wang, R Fan, X Liu, W Zhang - Frontiers in genetics, 2023 - frontiersin.org
Background: Most patients with idiopathic pulmonary fibrosis (IPF) have poor prognosis;
Effective predictive models for these patients are currently lacking. Epithelial–mesenchymal …
Effective predictive models for these patients are currently lacking. Epithelial–mesenchymal …
Screening of biomarkers involved in idiopathic pulmonary fibrosis and regulation of upstream miRNAs
L Gao, P Li, H Tian, M Wu, J Yang, X Xu - The American Journal of the …, 2022 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is the most common type of fatal interstitial
lung disease and IPF patients usually have a poor prognosis. Biomarkers that can predict …
lung disease and IPF patients usually have a poor prognosis. Biomarkers that can predict …
Consensus gene co-expression network analysis identifies novel genes associated with severity of fibrotic lung disease
Idiopathic pulmonary fibrosis (IPF) is a severe fibrotic lung disease characterized by
irreversible scarring of the lung parenchyma leading to dyspnea, progressive decline in lung …
irreversible scarring of the lung parenchyma leading to dyspnea, progressive decline in lung …