[HTML][HTML] Identification and validation of autophagy-related gene expression for predicting prognosis in patients with idiopathic pulmonary fibrosis

G Huang, X Xu, C Ju, N Zhong, J He… - Frontiers in …, 2022 - frontiersin.org
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal fibrotic
pulmonary disease with unknow etiology. Owing to lack of reliable prognostic biomarkers …

Molecular pathogenesis involved in human idiopathic pulmonary fibrosis based on an integrated microRNA‑mRNA interaction network

L Wang, W Huang, L Zhang… - Molecular medicine …, 2018 - spandidos-publications.com
Idiopathic pulmonary fibrosis (IPF) is considered to be an ailment of the lungs that cannot be
cured, wherein the lung tissues are characterized by increased thickness and stiffness …

Construction and validation of a bronchoalveolar lavage cell-associated gene signature for prognosis prediction in idiopathic pulmonary fibrosis

Y Xia, C Lei, D Yang, H Luo - International Immunopharmacology, 2021 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung
disease. It is urgent to identify biomarkers to precisely predict mortality. Methods: Gene …

Development and validation of a novel gene signature for predicting the prognosis of idiopathic pulmonary fibrosis based on three epithelial-mesenchymal transition …

J Zheng, H Dong, T Zhang, J Ning, Y Xu, C Cai - Frontiers in Genetics, 2022 - frontiersin.org
Background: Increasing evidence has revealed that epithelial–mesenchymal transition
(EMT) and immunity play key roles in idiopathic pulmonary fibrosis (IPF). However …

Exploring the Role of Biomarkers Associated with Alveolar Damage and Dysfunction in Idiopathic Pulmonary Fibrosis—A Systematic Review

AS Zamfir, ML Zabara, RI Arcana… - Journal of Personalized …, 2023 - mdpi.com
Background: Idiopathic pulmonary fibrosis (IPF) is one of the most aggressive forms of
interstitial lung diseases (ILDs), marked by an ongoing, chronic fibrotic process within the …

A functional genomic model for predicting prognosis in idiopathic pulmonary fibrosis

Y Huang, SF Ma, R Vij, JM Oldham… - BMC pulmonary …, 2015 - Springer
Background The course of disease for patients with idiopathic pulmonary fibrosis (IPF) is
highly heterogeneous. Prognostic models rely on demographic and clinical characteristics …

A validated hypoxia-inducible factor (HIF) signature across tissue compartments predicts clinical outcome in human lung fibrosis

Y Zhou, RM Ewing, DE Davies, Y Wang, MG Jones - medRxiv, 2022 - medrxiv.org
We previously reported that oxidative stress drives pseudohypoxic hypoxia-inducible factor
(HIF) pathway activation to promote pathogenetic collagen structure-function in human lung …

Biomarkers and their potential functions in idiopathic pulmonary fibrosis

S Ni, M Song, W Guo, T Guo, Q Shen… - Expert Review of …, 2020 - Taylor & Francis
Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic, devastating, and progressive
lung disease that is characterized by fibrosis and respiratory failure. IPF holds high morbidity …

Oxidative stress-linked biomarkers in idiopathic pulmonary fibrosis: A systematic review and meta-analysis

P Paliogiannis, AG Fois, C Collu, A Bandinu… - Biomarkers in …, 2018 - Future Medicine
Aim: The aim of this meta-analysis was to investigate associations between idiopathic
pulmonary fibrosis (IPF) and markers of oxidative stress (OS) measured in different …

Combining single-cell RNA sequencing data and transcriptomic data to unravel potential mechanisms and signature genes of the progression of idiopathic pulmonary …

X Zhou, F Tan, S Zhang, T Zhang - Functional & Integrative Genomics, 2023 - Springer
Patients with idiopathic pulmonary fibrosis (IPF) have a significantly higher prevalence of
lung adenocarcinoma (LUAD) than normal subjects, although the underlying association is …