Biomarkers of cellular senescence in idiopathic pulmonary fibrosis
Z Aversa, EJ Atkinson, EM Carmona, TA White… - Respiratory …, 2023 - Springer
Background Cellular senescence is a cell fate in response to diverse forms of age-related
damage and stress that has been implicated in the pathogenesis of idiopathic pulmonary …
damage and stress that has been implicated in the pathogenesis of idiopathic pulmonary …
Integrative analyses for the identification of idiopathic pulmonary fibrosis-associated genes and shared loci with other diseases
Background Although genome-wide association studies (GWAS) have identified many
genomic regions associated with idiopathic pulmonary fibrosis (IPF), the causal genes and …
genomic regions associated with idiopathic pulmonary fibrosis (IPF), the causal genes and …
Identifying a survival-associated cell type based on multi-level transcriptome analysis in idiopathic pulmonary fibrosis
F Xu, Y Tong, W Yang, Y Cai, M Yu, L Liu, Q Meng - Respiratory Research, 2024 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a progressive disease with a five-year
survival rate of less than 40%. There is significant variability in survival time among IPF …
survival rate of less than 40%. There is significant variability in survival time among IPF …
[HTML][HTML] Identification of three hub genes related to the prognosis of idiopathic pulmonary fibrosis using bioinformatics analysis
E Wang, Y Wang, S Zhou, X Xia, R Han… - … Journal of Medical …, 2022 - ncbi.nlm.nih.gov
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic respiratory disease
characterized by peripheral distribution of bilateral pulmonary fibrosis that is more …
characterized by peripheral distribution of bilateral pulmonary fibrosis that is more …
Integrated genomics reveals convergent transcriptomic networks underlying chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis
Rationale: Despite shared environmental exposures, idiopathic pulmonary fibrosis (IPF) and
chronic obstructive pulmonary disease are usually studied in isolation, and the presence of …
chronic obstructive pulmonary disease are usually studied in isolation, and the presence of …
Immune characteristics analysis and transcriptional regulation prediction based on gene signatures of chronic obstructive pulmonary disease
H Yu, W Guo, Y Liu, Y Wang - International journal of chronic …, 2021 - Taylor & Francis
Purpose The variation in inflammation in chronic obstructive pulmonary disease (COPD)
between individuals is genetically determined. This study aimed to identify gene signatures …
between individuals is genetically determined. This study aimed to identify gene signatures …
[HTML][HTML] Identification and validation of chemokine system-related genes in idiopathic pulmonary fibrosis
T Zhao, X Wu, X Zhao, K Yao, X Li, J Ni - Frontiers in Immunology, 2023 - frontiersin.org
Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung
disease with limited therapeutic options. Recent studies have demonstrated that …
disease with limited therapeutic options. Recent studies have demonstrated that …
Machine Learning and Single-Cell Analysis Identify Molecular Features of IPF-Associated Fibroblast Subtypes and Their Implications on IPF Prognosis
J Hou, Y Yang, X Han - International Journal of Molecular Sciences, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease of unknown cause, and the
involvement of fibroblasts in its pathogenesis is well recognized. However, a comprehensive …
involvement of fibroblasts in its pathogenesis is well recognized. However, a comprehensive …
Identification of Hub Genes in Idiopathic Pulmonary Fibrosis and Their Association with Lung Cancer by Bioinformatics Analysis
JM Velázquez-Enríquez, I Reyes-Avendaño… - … in Respiratory Medicine, 2023 - mdpi.com
Highlights What are the main findings? Identification of 1888 differentially expressed genes
(DEGs) related to idiopathic pulmonary fibrosis (IPF), including 1105 upregulated and 783 …
(DEGs) related to idiopathic pulmonary fibrosis (IPF), including 1105 upregulated and 783 …
Detecting the molecular system signatures of idiopathic pulmonary fibrosis through integrated genomic analysis
I Gangwar, N Kumar Sharma, G Panzade, S Awasthi… - Scientific reports, 2017 - nature.com
Abstract Idiopathic Pulmonary Fibrosis (IPF) is an incurable progressive fibrotic disease of
the lungs. We currently lack a systematic understanding of IPF biology and a systems …
the lungs. We currently lack a systematic understanding of IPF biology and a systems …