Background Non-fatal outcomes of disease and injury increasingly detract from the ability of
the world's population to live in full health, a trend largely attributable to an epidemiological …

Background The identification of modifiable risk factors for Alzheimer's disease is paramount
for early prevention and the targeting of new interventions. We aimed to assess the …

The latest estimates and analyses from the Global Burden of Disease Study 2015 (GBD
2015) 1–7 provide a vital link between the Millennium Development Goals (MDGs) and the …

Summary At present, about 33· 9 million people worldwide have Alzheimer's disease (AD),
and prevalence is expected to triple over the next 40 years. The aim of this Review was to …

Background Studies have suggested that the prevalence of dementia is lower in developing
than in developed regions. We investigated the prevalence and severity of dementia in sites …

Background: Measurement of changes in health across locations is useful to compare and
contrast changing epidemiological patterns against health system performance and identify …

Summary Background China and India jointly account for 38% of the world population, so
understanding the burden attributed to mental, neurological, and substance use disorders …

Background: We projected global trends in ischemic stroke from 2020 to 2030 according to
age, sex, and socio-demographic index (SDI) quintile. Methods: Estimated annual …

Background Documentation of patterns and long-term trends in mortality in young people,
which reflect huge changes in demographic and social determinants of adolescent health …

Background Brain and CNS cancers (collectively referred to as CNS cancers) are a source
of mortality and morbidity for which diagnosis and treatment require extensive resource …