Biomarkers in sarcopenia: a multifactorial approach

F Curcio, G Ferro, C Basile, I Liguori, P Parrella… - Experimental …, 2016 - Elsevier
The slow and continuous loss of muscle mass that progresses with aging is defined as
“sarcopenia”. Sarcopenia represents an important public health problem, being closely …

Sarcopenia: assessment of disease burden and strategies to improve outcomes

I Liguori, G Russo, L Aran, G Bulli, F Curcio… - … interventions in aging, 2018 - Taylor & Francis
Life expectancy is increasing worldwide, with a resultant increase in the elderly population.
Aging is characterized by the progressive loss of skeletal muscle mass and strength–a …

Biomarkers of sarcopenia in clinical trials—recommendations from the International Working Group on Sarcopenia

M Cesari, RA Fielding, M Pahor, B Goodpaster… - Journal of cachexia …, 2012 - Springer
Sarcopenia, the age-related skeletal muscle decline, is associated with relevant clinical and
socioeconomic negative outcomes in older persons. The study of this phenomenon and the …

The biological foundations of sarcopenia: established and promising markers

M Casati, AS Costa, D Capitanio, L Ponzoni… - Frontiers in …, 2019 - frontiersin.org
Sarcopenia, the progressive loss of muscle mass and strength, is one of the major health
issues in older adults, given its high prevalence accompanied by huge clinical and …

The “BIOmarkers associated with Sarcopenia and PHysical frailty in EldeRly pErsons”(BIOSPHERE) study: Rationale, design and methods

R Calvani, A Picca, F Marini, A Biancolillo… - European Journal of …, 2018 - Elsevier
Sarcopenia, the progressive and generalised loss of muscle mass and strength/function, is a
major health issue in older adults given its high prevalence and burdensome clinical …

Sarcopenia: a predictor of mortality and the need for early diagnosis and intervention

LI Filippin, VNO Teixeira, MPM da Silva… - Aging clinical and …, 2015 - Springer
The term sarcopenia refers to the loss of muscle mass that occurs with aging. Sarcopenia is
defined by the European Working Group on Sarcopenia in Older People (EWGSOP) as low …

Biomarkers for physical frailty and sarcopenia

R Calvani, F Marini, M Cesari, M Tosato… - Aging clinical and …, 2017 - Springer
Physical frailty (PF) and sarcopenia are major health issues in geriatric populations, given
their high prevalence and association with several adverse outcomes. Nevertheless, the …

Sarcopenia and functional decline: pathophysiology, prevention and therapy

I Bautmans, K Van Puyvelde, T Mets - Acta Clinica Belgica, 2009 - Taylor & Francis
Twenty years ago, the term 'sarcopenia'has been introduced to describe the ageing related
loss of skeletal muscle mass. Since then, sarcopenia has been intensively studied and …

Biomarkers for physical frailty and sarcopenia: state of the science and future developments

R Calvani, F Marini, M Cesari, M Tosato… - Journal of cachexia …, 2015 - Wiley Online Library
Physical frailty and sarcopenia are two common and largely overlapping geriatric conditions
upstream of the disabling cascade. The lack of a unique operational definition for physical …

Sarcopenia–The search for emerging biomarkers

A Kalinkovich, G Livshits - Ageing research reviews, 2015 - Elsevier
Sarcopenia, an age-related decline in skeletal muscle mass and function, dramatically
affects the life quality of elder people. In view of increasing life expectancy, sarcopenia …