Dysfunction of central dopaminergic neurotransmission has been implicated in a series of
neuropsychiatric disorders, including Tourette's syndrome, schizophrenia, and drug and …

Dysfunction of central dopaminergic neurotransmission has been implicated in the
pathogenesis of schizophrenia as well as drug and alcohol dependence. Different drugs of …

The involvement of dopamine in drug reinforcement is well recognized but its role in drug
addiction is much less clear. Imaging studies have shown that the reinforcing effects of drugs …

A dysregulation of the mesolimbic dopamine system in schizophrenia patients may lead to
aberrant attribution of incentive salience and contribute to the emergence of …

A novel mechanism for regulating dopamine activity in subcortical sites and its possible
relevance to schizophrenia is proposed. This hypothesis is based on the regulation of …

This chapter is an update on the dopamine (DA) imbalance in schizophrenia, including the
evidence for subcortical hyperstimulation of D2 receptors underlying positive symptoms and …

Elevated in vivo markers of presynaptic striatal dopamine activity have been a consistent
finding in schizophrenia, and include a large effect size elevation in dopamine synthesis …

Presynaptic dopamine (DA) transmission has been measured in schizophrenia using
different paradigms aimed at providing estimates of the integrity or the activity of the …

Dopamine has undergone extensive investigation due to its known involvement in a number
of neurological and psychiatric disorders. In particular, studies into pathological conditions …

Disrupted salience processing is proposed as central in linking dysregulated dopamine
function with psychotic symptoms. Several strands of evidence are now converging in …