Rapidly growing evidences link maternal lifestyle and prenatal factors with serious health
consequences and diseases later in life. Extensive epidemiological studies have identified a …

Literature on maternal exposures and the risk of epigenetic changes or diseases in the
offspring is growing. Paternal contributions are often not considered. However, some animal …

There is accumulating evidence that many chronic diseases such as type 2 diabetes and
coronary heart disease might originate during early life. This evidence gives rise to the …

Winner of 2016 BMA Medical Award for Basic and Clinical Sciences The Epigenome and
Developmental Origins of Health and Disease synthesizes the existing knowledge on how …

Abundant evidence exists linking maternal and paternal environments from
pericopconception through the postnatal period to later risk to offspring diseases. This …

The concept of developmental origins of diseases has gained a huge interest in recent years
and is a constantly emerging scientific field. First observations hereof originated from …

Maternal and paternal factors influence offspring development and program its genome for
successful postnatal life. Based on the stressors during gestation, the pregnant female …

Although cells of an individual generally all have the same DNA, each cell type has a unique
pattern of active (expressed) and inactive genes. These patterns are established or …

Fetal growth is determined by the interaction between the environment and the fetal
genome. The fetal environment, in turn, is determined by the maternal environment and by …

Abstract The literature about Developmental Origins of Health and Disease (DOHaD)
studies is considerably growing. Maternal and paternal environment, during all the …