Maternal and paternal factors influence offspring development and program its genome for
successful postnatal life. Based on the stressors during gestation, the pregnant female …

The concept of developmental origins of diseases has gained a huge interest in recent years
and is a constantly emerging scientific field. First observations hereof originated from …

Rapidly growing evidences link maternal lifestyle and prenatal factors with serious health
consequences and diseases later in life. Extensive epidemiological studies have identified a …

Although cells of an individual generally all have the same DNA, each cell type has a unique
pattern of active (expressed) and inactive genes. These patterns are established or …

Literature on maternal exposures and the risk of epigenetic changes or diseases in the
offspring is growing. Paternal contributions are often not considered. However, some animal …

Abstract The literature about Developmental Origins of Health and Disease (DOHaD)
studies is considerably growing. Maternal and paternal environment, during all the …

Abundant evidence exists linking maternal and paternal environments from
pericopconception through the postnatal period to later risk to offspring diseases. This …

The level of transcriptional activity of a gene is regulated by epigenetic processes. There is
compelling evidence that environmental challenges throughout the life course can induce …

Racial and/or ethnic minorities carry the highest burden of many adverse health outcomes
intergenerationally. We propose a paradigm in which developmental programming …

Health consequences of relative or absolute poverty constitute a definitive area of study in
social medicine. As demonstrated in the extreme example of the Dutch Hunger Winter from …