[HTML][HTML] Macrophage targeted theranostics as personalized nanomedicine strategies for inflammatory diseases

SK Patel, JM Janjic - Theranostics, 2015 - ncbi.nlm.nih.gov
Inflammatory disease management poses challenges due to the complexity of inflammation
and inherent patient variability, thereby necessitating patient-specific therapeutic …

Nanomedicines for dysfunctional macrophage-associated diseases

H He, S Ghosh, H Yang - Journal of Controlled Release, 2017 - Elsevier
Macrophages play vital functions in host inflammatory reaction, tissue repair, homeostasis
and immunity. Dysfunctional macrophages have significant pathophysiological impacts on …

Imaging macrophages with nanoparticles

R Weissleder, M Nahrendorf, MJ Pittet - Nature materials, 2014 - nature.com
Nanomaterials have much to offer, not only in deciphering innate immune cell biology and
tracking cells, but also in advancing personalized clinical care by providing diagnostic and …

[HTML][HTML] Biomimetic nanoparticles with enhanced affinity towards activated endothelium as versatile tools for theranostic drug delivery

JO Martinez, R Molinaro, KA Hartman, C Boada… - Theranostics, 2018 - ncbi.nlm.nih.gov
Activation of the vascular endothelium is characterized by increased expression of vascular
adhesion molecules and chemokines. This activation occurs early in the progression of …

Multifunctional nanoparticles for multimodal imaging and theragnosis

DE Lee, H Koo, IC Sun, JH Ryu, K Kim… - Chemical Society …, 2012 - pubs.rsc.org
Nanomedicine is the biomedical application of nanoscale materials for diagnosis and
therapy of disease. Recent advances in nanotechnology and biotechnology have …

Applying nanomedicine in maladaptive inflammation and angiogenesis

A Alaarg, C Pérez-Medina, JM Metselaar… - Advanced drug delivery …, 2017 - Elsevier
Inflammation and angiogenesis drive the development and progression of multiple
devastating diseases such as atherosclerosis, cancer, rheumatoid arthritis, and inflammatory …

[HTML][HTML] Biomimetic nanoparticles for inflammation targeting

K Jin, Z Luo, B Zhang, Z Pang - Acta Pharmaceutica Sinica B, 2018 - Elsevier
There have been many recent exciting developments in biomimetic nanoparticles for
biomedical applications. Inflammation, a protective response involving immune cells, blood …

[HTML][HTML] Neutrophils and macrophages as targets for development of nanotherapeutics in inflammatory diseases

Y Su, J Gao, P Kaur, Z Wang - Pharmaceutics, 2020 - mdpi.com
Neutrophils and macrophages are major components of innate systems, playing central
roles in inflammation responses to infections and tissue injury. If they are out of control …

Theranostic nanoparticles for future personalized medicine

JH Ryu, S Lee, S Son, SH Kim, JF Leary, K Choi… - Journal of controlled …, 2014 - Elsevier
The concept of personalized medicine has recently emerged as a promising way to address
unmet medical needs. Due to the limitations of standard diagnostic and therapeutic …

[HTML][HTML] Nanomedicine therapies modulating macrophage dysfunction: a potential strategy to attenuate cytokine storms in severe infections

J Liu, M Wan, CJ Lyon, TY Hu - Theranostics, 2020 - ncbi.nlm.nih.gov
Cytokine storms, defined by the dysregulated and excessive production of multiple pro-
inflammatory cytokines, are closely associated with the pathology and mortality of several …