Efficacy of new-generation antidepressants assessed with the Montgomery-Asberg Depression Rating Scale, the gold standard clinician rating scale: A meta-analysis …

MP Hengartner, JC Jakobsen, A Sørensen, M Plöderl - PLoS One, 2020 - journals.plos.org
Background It has been claimed that efficacy estimates based on the Hamilton Depression
Rating-Scale (HDRS) underestimate antidepressants true treatment effects due to the …

Estimates of the minimal important difference to evaluate the clinical significance of antidepressants in the acute treatment of moderate-to-severe depression

MP Hengartner, M Plöderl - BMJ evidence-based medicine, 2022 - ebm.bmj.com
The efficacy of antidepressants in the acute treatment of moderate-to-severe depression
remains a controversial issue. The minimal important difference (MID) is relevant to judge …

A review of studies of the Montgomery–Asberg Depression Rating Scale in controls: implications for the definition of remission in treatment studies of depression

M Zimmerman, I Chelminski… - International clinical …, 2004 - journals.lww.com
Abstract The Montgomery–Asberg Depression Rating Scale (MADRS) is one of the most
commonly used symptom severity scales to evaluate the efficacy of antidepressant …

Do side effects of antidepressants impact efficacy estimates based on the Hamilton Depression Rating Scale? A pooled patient-level analysis

F Hieronymus, A Lisinski, E Eriksson… - Translational …, 2021 - nature.com
Abstract The Hamilton Depression Rating Scale (HDRS-17) measures symptoms that may
overlap with common antidepressant side effects (eg, sexual dysfunction), thus making it …

What are the treatment remission, response and extent of improvement rates after up to four trials of antidepressant therapies in real-world depressed patients? A …

HE Pigott, T Kim, C Xu, I Kirsch, J Amsterdam - BMJ open, 2023 - bmjopen.bmj.com
Objective Reanalyse the patient-level data set of the Sequenced Treatment Alternatives to
Relieve Depression (STAR* D) study with fidelity to the original research protocol and …

Randomized clinical trials underestimate the efficacy of antidepressants in less severe depression

G Isacsson, M Adler - Acta Psychiatrica Scandinavica, 2012 - Wiley Online Library
Isacsson G, Adler M. Randomized clinical trials underestimate the efficacy of
antidepressants in less severe depression. Objective: Demonstrating the superiority of …

Relative sensitivity of the Montgomery–Åsberg depression rating scale, the Hamilton depression rating scale and the Clinical Global Impressions rating scale in …

A Khan, AE Brodhead, RL Kolts - International clinical …, 2004 - journals.lww.com
The present study replicates a previous study in which we found that the less frequently
used Montgomery–Åsberg Depression Rating Scale (MADRS) is as sensitive an instrument …

Sensitivity of the Montgomery Asberg Depression Rating Scale to response and its consequences for the assessment of efficacy

G Santen, M Danhof, O Della Pasqua - Journal of psychiatric research, 2009 - Elsevier
An increasing body of evidence is available suggesting that the Hamilton Depression Rating
Scale (HAMD) is not a sensitive measure of treatment effect. In this investigation, we explore …

The self-reported Montgomery-Åsberg depression rating scale is a useful evaluative tool in major depressive disorder

B Fantino, N Moore - BMC psychiatry, 2009 - Springer
Abstract Background The use of Patient-reported Outcomes (PROs) as secondary endpoints
in the development of new antidepressants has grown in recent years. The objective of this …

Not as golden as standards should be: interpretation of the Hamilton Rating Scale for Depression

L Kriston, A von Wolff - Journal of affective disorders, 2011 - Elsevier
BACKGROUND: The Hamilton Rating Scale for Depression (HRSD) is one of the most
frequently used instruments in antidepressant trials. METHODS: We examined different …