Dose heterogeneity in the target volume and intensity-modulated radiotherapy to escalate the dose in the treatment of non–small-cell lung cancer

M Schwarz, M Alber, JV Lebesque, BJ Mijnheer… - International Journal of …, 2005 - Elsevier
Purpose: To quantify the dose escalation achievable in the treatment of non-small-cell lung
cancer (NSCLC) by allowing dose heterogeneity in the target volume or using intensity …

Dose and volume reduction for normal lung using intensity-modulated radiotherapy for advanced-stage non–small-cell lung cancer

H Murshed, HH Liu, Z Liao, JL Barker, X Wang… - International Journal of …, 2004 - Elsevier
PURPOSE: To investigate dosimetric improvements with respect to tumor-dose conformity
and normal tissue sparing using intensity-modulated radiotherapy (IMRT) compared with …

Feasibility of sparing lung and other thoracic structures with intensity-modulated radiotherapy for non–small-cell lung cancer

HH Liu, X Wang, L Dong, Q Wu, Z Liao… - International Journal of …, 2004 - Elsevier
PURPOSE: To investigate the possibility of using intensity-modulated radiotherapy (IMRT) to
reduce the irradiated volumes of the normal lung and other critical structures in the treatment …

Potential for reduced toxicity and dose escalation in the treatment of inoperable non–small-cell lung cancer: A comparison of intensity-modulated radiation therapy …

IS Grills, D Yan, AA Martinez, FA Vicini… - International Journal of …, 2003 - Elsevier
PURPOSE: To systematically evaluate four different techniques of radiation therapy (RT)
used to treat non–small-cell lung cancer and to determine their efficacy in meeting multiple …

Inhomogeneous target-dose distributions: A dimension more for optimization?

WRT De Gersem, S Derycke, CO Colle… - International Journal of …, 1999 - Elsevier
Purpose: To evaluate if the use of inhomogeneous target-dose distributions, obtained by 3D
conformal radiotherapy plans with or without beam intensity modulation, offers the possibility …

[HTML][HTML] Dosimetric advantages of intensity modulated radiation therapy in locally advanced lung cancer

J Boyle, B Ackerson, L Gu, CR Kelsey - Advances in Radiation Oncology, 2017 - Elsevier
Purpose Radiation therapy plays an essential role in the treatment of locally advanced lung
cancer, but it inevitably leads to incidental and unnecessary dose to critical organs …

Non-coplanar beam intensity modulation allows large dose escalation in stage III lung cancer

S Derycke, B Van Duyse, W De Gersem… - Radiotherapy and …, 1997 - Elsevier
Purpose: To evaluate the feasibility of dose escalation in stage III non-small cell lung cancer,
we compared standard coplanar (2D) with non-coplanar beam arrangements, without (3D) …

High-dose radiotherapy in inoperable nonsmall cell lung cancer: comparison of volumetric modulated arc therapy, dynamic IMRT and 3D conformal radiotherapy.

B Id, MG Van Hinsberg… - Medical Dosimetry: Official …, 2012 - europepmc.org
Conformal 3D radiotherapy (3D-CRT) combined with chemotherapy for inoperable non-
small cell lung cancer (NSCLC) to the preferable high dose is often not achievable because …

Intensity-modulated radiotherapy for locally advanced non–small-cell lung cancer: a dose-escalation planning study

Y Lievens, A Nulens, MA Gaber, G Defraene… - International Journal of …, 2011 - Elsevier
PURPOSE: To evaluate the potential for dose escalation with intensity-modulated
radiotherapy (IMRT) in positron emission tomography-based radiotherapy planning for …

Intraindividual comparison of conventional three-dimensional radiotherapy and intensity modulated radiotherapy in the therapy of locally advanced non-small cell lung …

S Marnitz, M Stuschke, J Bohsung… - Strahlentherapie …, 2002 - search.proquest.com
Local failure is the one of the most frequent cause of tumor related death in locally advanced
non-small cell lung cancer (LAD-NSCLC). Dose escalation has the promise of increased …