[HTML][HTML] Evaluation of secretion prediction highlights differing approaches needed for oomycete and fungal effectors

J Sperschneider, AH Williams, JK Hane… - Frontiers in plant …, 2015 - frontiersin.org
The steadily increasing number of sequenced fungal and oomycete genomes has enabled
detailed studies of how these eukaryotic microbes infect plants and cause devastating …

EffectorP: predicting fungal effector proteins from secretomes using machine learning

J Sperschneider, DM Gardiner, PN Dodds… - New …, 2016 - Wiley Online Library
Eukaryotic filamentous plant pathogens secrete effector proteins that modulate the host cell
to facilitate infection. Computational effector candidate identification and subsequent …

EffectorP 3.0: prediction of apoplastic and cytoplasmic effectors in fungi and oomycetes

J Sperschneider, PN Dodds - Molecular plant-microbe …, 2022 - Am Phytopath Society
Many fungi and oomycete species are devasting plant pathogens. These eukaryotic
filamentous pathogens secrete effector proteins to facilitate plant infection. Fungi and …

Improved prediction of fungal effector proteins from secretomes with EffectorP 2.0

J Sperschneider, PN Dodds… - Molecular plant …, 2018 - Wiley Online Library
Plant‐pathogenic fungi secrete effector proteins to facilitate infection. We describe extensive
improvements to EffectorP, the first machine learning classifier for fungal effector prediction …

[HTML][HTML] An automated and combinative method for the predictive ranking of candidate effector proteins of fungal plant pathogens

DAB Jones, L Rozano, JW Debler, RL Mancera… - Scientific reports, 2021 - nature.com
Fungal plant-pathogens promote infection of their hosts through the release of 'effectors'—a
broad class of cytotoxic or virulence-promoting molecules. Effectors may be recognised by …

[HTML][HTML] Computational prediction of effector proteins in fungi: opportunities and challenges

H Sonah, RK Deshmukh, RR Bélanger - Frontiers in plant science, 2016 - frontiersin.org
Effector proteins are mostly secretory proteins that stimulate plant infection by manipulating
the host response. Identifying fungal effector proteins and understanding their function is of …

[HTML][HTML] EffHunter: A tool for prediction of effector protein candidates in fungal proteomic databases

KG Carreón-Anguiano, I Islas-Flores, J Vega-Arreguín… - Biomolecules, 2020 - mdpi.com
Pathogens are able to deliver small-secreted, cysteine-rich proteins into plant cells to enable
infection. The computational prediction of effector proteins remains one of the most …

[HTML][HTML] Effector biology of biotrophic plant fungal pathogens: Current advances and future prospects

R Jaswal, K Kiran, S Rajarammohan, H Dubey… - Microbiological …, 2020 - Elsevier
The interaction of fungal pathogens with their host requires a novel invading mechanism
and the presence of various virulence-associated components responsible for promoting the …

Prediction of effector proteins and their implications in pathogenicity of phytopathogenic filamentous fungi: a review

Y Wu, L Xie, Y Jiang, T Li - International Journal of Biological …, 2022 - Elsevier
Plant pathogenic fungi encode and secrete effector proteins to promote pathogenesis. In
recent years, the important role of effector proteins in fungi and plant host interactions has …

POOE: predicting oomycete effectors based on a pre-trained large protein language model

M Zhao, C Lei, K Zhou, Y Huang, C Fu, S Yang… - Msystems, 2024 - Am Soc Microbiol
Oomycetes are fungus-like eukaryotic microorganisms which can cause catastrophic
diseases in many plants. Successful infection of oomycetes depends highly on their effector …