Rapid uptake of gold nanorods by primary human blood phagocytes and immunomodulatory effects of surface chemistry
M Bartneck, HA Keul, S Singh, K Czaja, J Bornemann… - ACS …, 2010 - ACS Publications
Nanoparticle-based in vivo applications should consider the omnipresence of the
phagocytes in the bloodstream and tissue. We have studied the nanoparticle uptake …
phagocytes in the bloodstream and tissue. We have studied the nanoparticle uptake …
Phagocytosis of biocompatible gold nanoparticles
We report the evidence for the cellular uptake of gold nanoparticles via the phagocytosis
mechanism in murine macrophage cells strongly supported by TEM and optical microscopy …
mechanism in murine macrophage cells strongly supported by TEM and optical microscopy …
Surface chemistry of gold nanoparticles mediates their exocytosis in macrophages
Significant quantities of synthetic nanoparticles circulating in the body are cleared and
retained for long periods of time in the resident macrophages of the mononuclear phagocytic …
retained for long periods of time in the resident macrophages of the mononuclear phagocytic …
Geometry and surface characteristics of gold nanoparticles influence their biodistribution and uptake by macrophages
Spherical and rod-shaped gold nanoparticles with surface poly (ethylene glycol)(PEG)
chains were characterized for size, shape, charge, poly dispersity and surface plasmon …
chains were characterized for size, shape, charge, poly dispersity and surface plasmon …
Fluorescence‐encoded gold nanoparticles: library design and modulation of cellular uptake into dendritic cells
L Rodriguez‐Lorenzo, K Fytianos, F Blank… - Small, 2014 - Wiley Online Library
In order to harness the unique properties of nanoparticles for novel clinical applications and
to modulate their uptake into specific immune cells we designed a new library of homo‐and …
to modulate their uptake into specific immune cells we designed a new library of homo‐and …
Macrophage Scavenger Receptor A Mediates The Uptake of Gold Colloids by Macrophages In Vitro
A França, P Aggarwal, EV Barsov, SV Kozlov… - …, 2011 - Taylor & Francis
Aims: While numerous studies have reported on nanoparticle uptake by phagocytic cells, the
mechanisms of this uptake are poorly understood. A metastudy of research focusing on …
mechanisms of this uptake are poorly understood. A metastudy of research focusing on …
Nanoparticle size and surface chemistry determine serum protein adsorption and macrophage uptake
Delivery and toxicity are critical issues facing nanomedicine research. Currently, there is
limited understanding and connection between the physicochemical properties of a …
limited understanding and connection between the physicochemical properties of a …
Uptake efficiency of surface modified gold nanoparticles does not correlate with functional changes and cytokine secretion in human dendritic cells in vitro
K Fytianos, L Rodriguez-Lorenzo, MJD Clift… - … , Biology and Medicine, 2015 - Elsevier
Engineering nanoparticles (NPs) for immune modulation require a thorough understanding
of their interaction (s) with cells. Gold NPs (AuNPs) were coated with polyethylene glycol …
of their interaction (s) with cells. Gold NPs (AuNPs) were coated with polyethylene glycol …
The interplay of size and surface functionality on the cellular uptake of sub-10 nm gold nanoparticles
Correlation of the surface physicochemical properties of nanoparticles with their interactions
with biosystems provides key foundational data for nanomedicine. We report here the …
with biosystems provides key foundational data for nanomedicine. We report here the …
Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells
BD Chithrani, AA Ghazani, WCW Chan - Nano letters, 2006 - ACS Publications
We investigated the intracellular uptake of different sized and shaped colloidal gold
nanoparticles. We showed that kinetics and saturation concentrations are highly dependent …
nanoparticles. We showed that kinetics and saturation concentrations are highly dependent …
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