Common neurogenetic diagnosis and meso-limbic manipulation of hypodopaminergic function in reward deficiency syndrome (RDS): Changing the recovery …
K Blum, M Febo, RD Badgaiyan… - Current …, 2017 - ingentaconnect.com
Background: In 1990, Blum and associates provided the first confirmed genetic link between
the DRD2 polymorphisms and alcoholism. This finding was based on an earlier conceptual …
the DRD2 polymorphisms and alcoholism. This finding was based on an earlier conceptual …
Hatching the behavioral addiction egg: Reward Deficiency Solution System (RDSS)™ as a function of dopaminergic neurogenetics and brain functional connectivity …
K Blum, M Febo, T McLaughlin, FJ Cronje… - Journal of Behavioral …, 2014 - akjournals.com
Background Following the first association between the dopamine D2 receptor gene
polymorphism and severe alcoholism, there has been an explosion of research reports in …
polymorphism and severe alcoholism, there has been an explosion of research reports in …
Relationship between dopaminergic neurotransmission, alcoholism, and reward deficiency syndrome
A Bowirrat, M Oscar‐Berman - American Journal of Medical …, 2005 - Wiley Online Library
In this review, we described the neural substrates underlying Reward Deficiency syndrome
which, in turn, is posited to underlie alcohol dependency. Alcoholism is a complex …
which, in turn, is posited to underlie alcohol dependency. Alcoholism is a complex …
[HTML][HTML] Neurogenetic impairments of brain reward circuitry links to reward deficiency syndrome (RDS): Potential nutrigenomic induced dopaminergic activation
K Blum, M Oscar-Berman, J Giordano… - Journal of genetic …, 2012 - ncbi.nlm.nih.gov
Work from our laboratory in both in-patient and outpatient facilities utilizing the
Comprehensive Analysis of Reported Drugs (CARD)™ found a significant lack of …
Comprehensive Analysis of Reported Drugs (CARD)™ found a significant lack of …
[HTML][HTML] Addiction by any other name is still addiction: Embracing molecular neurogenetic/epigenetic basis of reward deficiency
D Edwards, AK Roy III, B Boyett… - Journal of addiction …, 2020 - ncbi.nlm.nih.gov
V AA uthor Man uscript creating phenotypical risk for pathological expression [1]. One of
these created phenotypes involves the molecular rearrangement of known base pairs sitting …
these created phenotypes involves the molecular rearrangement of known base pairs sitting …
Introducing precision addiction management of reward deficiency syndrome, the construct that underpins all addictive behaviors
Following almost three decades of genetic-based research related to identifying and
characterizing addiction-related Reward Deficiency Syndrome (RDS), a paradigm shift is …
characterizing addiction-related Reward Deficiency Syndrome (RDS), a paradigm shift is …
Should reward deficiency syndrome (RDS) be considered an umbrella disorder for mental illness and associated genetic and epigenetic induced dysregulation of …
K Blum, CA Dennen, I Elman, A Bowirrat… - Journal of Personalized …, 2022 - mdpi.com
Reward Deficiency Syndrome (RDS) is defined as a breakdown of reward
neurotransmission that results in a wide range of addictive, compulsive, and impulsive …
neurotransmission that results in a wide range of addictive, compulsive, and impulsive …
The reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive and compulsive behaviors
K Blum, ER Braverman, JM Holder… - … of psychoactive drugs, 2000 - Taylor & Francis
The dopaminergic system, and in particular the dopamine D2 receptor, has been implicated
in reward mechanisms. The net effect of neurotransmitter interaction at the mesolimbic brain …
in reward mechanisms. The net effect of neurotransmitter interaction at the mesolimbic brain …
[HTML][HTML] Molecular genetic testing in reward deficiency syndrome (RDS): Facts and fiction
K Blum, RD Badgaiyan, G Agan… - Journal of reward …, 2015 - ncbi.nlm.nih.gov
Background The Brain Reward Cascade (BRC) is an interaction of neurotransmitters and
their respective genes to control the amount of dopamine released within the brain. Any …
their respective genes to control the amount of dopamine released within the brain. Any …
Clinically combating reward deficiency syndrome (RDS) with dopamine agonist therapy as a paradigm shift: dopamine for dinner?
Everyday, there are several millions of people that are increasingly unable to combat their
frustrating and even fatal romance with getting high and/or experiencing “normal” feelings of …
frustrating and even fatal romance with getting high and/or experiencing “normal” feelings of …