[HTML][HTML] Imidazoles as potential anticancer agents: an update on recent studies
P Sharma, C LaRosa, J Antwi, R Govindarajan… - Molecules, 2021 - mdpi.com
Nitrogen-containing heterocyclic rings are common structural components of marketed
drugs. Among these heterocycles, imidazole/fused imidazole rings are present in a wide …
drugs. Among these heterocycles, imidazole/fused imidazole rings are present in a wide …
Imidazoles as potential anticancer agents
Cancer is a black spot on the face of humanity in this era of science and technology.
Presently, several classes of anticancer drugs are available in the market, but issues such …
Presently, several classes of anticancer drugs are available in the market, but issues such …
Comprehensive review in current developments of imidazole‐based medicinal chemistry
L Zhang, XM Peng, GLV Damu… - Medicinal research …, 2014 - Wiley Online Library
Imidazole ring is an important five‐membered aromatic heterocycle widely present in natural
products and synthetic molecules. The unique structural feature of imidazole ring with …
products and synthetic molecules. The unique structural feature of imidazole ring with …
Imidazole as a promising medicinal scaffold: Current status and future direction
SS Alghamdi, RS Suliman, K Almutairi… - Drug Design …, 2021 - Taylor & Francis
Various imidazole-containing compounds have been tested for their medical usefulness in
clinical trials for several disease conditions. The rapid expansion of imidazole-based …
clinical trials for several disease conditions. The rapid expansion of imidazole-based …
Imidazole: having versatile biological activities
Imidazoles have occupied a unique position in heterocyclic chemistry, and its derivatives
have attracted considerable interests in recent years for their versatile properties in …
have attracted considerable interests in recent years for their versatile properties in …
Naturally occurring and synthetic imidazoles: Their chemistry and their biological activities
LD Luca - Current medicinal chemistry, 2006 - ingentaconnect.com
Imidazoles are an important class of heterocycles and include many substances of both
biological and chemical interest. They are part of a large number of highly significant …
biological and chemical interest. They are part of a large number of highly significant …
[HTML][HTML] Synthesis and therapeutic potential of imidazole containing compounds
Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen,
four hydrogen atoms, and two double bonds. It is also known as 1, 3-diazole. It contains two …
four hydrogen atoms, and two double bonds. It is also known as 1, 3-diazole. It contains two …
[HTML][HTML] Imidazole: synthesis, functionalization and physicochemical properties of a privileged structure in medicinal chemistry
HV Tolomeu, CAM Fraga - Molecules, 2023 - mdpi.com
Imidazole was first synthesized by Heinrich Debus in 1858 and was obtained by the reaction
of glyoxal and formaldehyde in ammonia, initially called glyoxaline. The current literature …
of glyoxal and formaldehyde in ammonia, initially called glyoxaline. The current literature …
Synthesis and biological evaluation of benzo [d] imidazole derivatives as potential anti-cancer agents
HM Alkahtani, AY Abbas, S Wang - Bioorganic & medicinal chemistry …, 2012 - Elsevier
We herein report the synthesis, biological activity and structure–activity relationship of
derivatives of 5, 6-dichloro-1-β-d-ribofuranosylbenzimidazole and benzo [d] imidazole. A …
derivatives of 5, 6-dichloro-1-β-d-ribofuranosylbenzimidazole and benzo [d] imidazole. A …
[PDF][PDF] Imidazole and its biological activities: A review
Imidazole is a planer five-member heterocyclic ring with 3C and 2N atom and in ring N is
present in 1 st and 3 rd positions. The imidazole ring is a constituent of several important …
present in 1 st and 3 rd positions. The imidazole ring is a constituent of several important …