Prevention of psychosis: advances in detection, prognosis, and intervention

P Fusar-Poli, GS De Pablo, CU Correll… - JAMA …, 2020 - jamanetwork.com
Importance Detection, prognosis, and indicated interventions in individuals at clinical high
risk for psychosis (CHR-P) are key components of preventive psychiatry. Objective To …

Lack of evidence to favor specific preventive interventions in psychosis: a network meta‐analysis

C Davies, A Cipriani, JPA Ioannidis, J Radua… - World …, 2018 - Wiley Online Library
Preventing psychosis in patients at clinical high risk may be a promising avenue for pre‐
emptively ameliorating outcomes of the most severe psychiatric disorder. However …

Clinical outcomes in individuals at clinical high risk of psychosis who do not transition to psychosis: a meta-analysis

GS De Pablo, L Soardo, A Cabras, J Pereira… - Epidemiology and …, 2022 - cambridge.org
Aims The clinical outcomes of individuals at clinical high risk of psychosis (CHR-P) who do
not transition to psychosis are heterogeneous and inconsistently reported. We aimed to …

Association of preceding psychosis risk states and non‐psychotic mental disorders with incidence of clinical psychosis in the general population: A prospective study …

S Guloksuz, LK Pries, M Ten Have, R de Graaf… - World …, 2020 - Wiley Online Library
The validity and clinical utility of the concept of “clinical high risk”(CHR) for psychosis have
so far been investigated only in risk‐enriched samples in clinical settings. In this population …

[HTML][HTML] Improving the detection of individuals at clinical risk for psychosis in the community, primary and secondary care: an integrated evidence-based approach

P Fusar-Poli, SA Sullivan, JL Shah… - Frontiers in psychiatry, 2019 - frontiersin.org
Background: The first rate-limiting step for improving outcomes of psychosis through
preventive interventions in people at clinical high risk for psychosis (CHR-P) is the ability to …

Preventive treatments for psychosis: umbrella review (just the evidence)

P Fusar-Poli, C Davies, M Solmi, N Brondino… - Frontiers in …, 2019 - frontiersin.org
Background: Indicated primary prevention in young people at Clinical High Risk for
Psychosis (CHR-P) is a promising avenue for improving outcomes of one of the most severe …

Probability of transition to psychosis in individuals at clinical high risk: an updated meta-analysis

GS De Pablo, J Radua, J Pereira, I Bonoldi… - JAMA …, 2021 - jamanetwork.com
Importance Estimating the current likelihood of transitioning from a clinical high risk for
psychosis (CHR-P) to psychosis holds paramount importance for preventive care and …

Efficacy and acceptability of interventions for attenuated positive psychotic symptoms in individuals at clinical high risk of psychosis: a network meta-analysis

C Davies, J Radua, A Cipriani, D Stahl… - Frontiers in …, 2018 - frontiersin.org
Background: Attenuated positive psychotic symptoms represent the defining features of the
clinical high-risk for psychosis (CHR-P) criteria. The effectiveness of each available …

At risk or not at risk? A meta‐analysis of the prognostic accuracy of psychometric interviews for psychosis prediction

P Fusar‐Poli, M Cappucciati, G Rutigliano… - World …, 2015 - Wiley Online Library
An accurate detection of individuals at clinical high risk (CHR) for psychosis is a prerequisite
for effective preventive interventions. Several psychometric interviews are available, but their …

Prognostic accuracy and clinical utility of psychometric instruments for individuals at clinical high-risk of psychosis: a systematic review and meta-analysis

D Oliver, M Arribas, J Radua, G Salazar de Pablo… - Molecular …, 2022 - nature.com
Accurate prognostication of individuals at clinical high-risk for psychosis (CHR-P) is an
essential initial step for effective primary indicated prevention. We aimed to summarise the …