Rethinking neuroprotection in severe traumatic brain injury: toward bedside neuroprotection
T Zoerle, M Carbonara, ER Zanier, F Ortolano… - Frontiers in …, 2017 - frontiersin.org
Neuroprotection after traumatic brain injury (TBI) is an important goal pursued strenuously in
the last 30 years. The acute cerebral injury triggers a cascade of biochemical events that …
the last 30 years. The acute cerebral injury triggers a cascade of biochemical events that …
Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies
Traumatic brain injury (TBI) causes secondary biochemical changes that contribute to
subsequent tissue damage and associated neuronal cell death. Neuroprotective treatments …
subsequent tissue damage and associated neuronal cell death. Neuroprotective treatments …
Neuroprotective strategies for traumatic brain injury: improving clinical translation
Traumatic brain injury (TBI) induces secondary biochemical changes that contribute to
delayed neuroinflammation, neuronal cell death, and neurological dysfunction. Attenuating …
delayed neuroinflammation, neuronal cell death, and neurological dysfunction. Attenuating …
Neuroprotection for traumatic brain injury
Traumatic brain injury (TBI) is a major cause of mortality and morbidity worldwide. Despite
extensive preclinical research supporting the effectiveness of neuroprotective therapies for …
extensive preclinical research supporting the effectiveness of neuroprotective therapies for …
Targets of neuroprotection and review of pharmacological interventions in traumatic brain injury
MI Hiskens - Journal of Pharmacology and Experimental …, 2022 - ASPET
Traumatic brain injury (TBI) is a major contributor to disability and death worldwide, and
manifests in cognitive, behavioral, and motor impairment. Although there have been …
manifests in cognitive, behavioral, and motor impairment. Although there have been …
Neuroprotection in traumatic brain injury: a complex struggle against the biology of nature
JW Schouten - Current opinion in critical care, 2007 - journals.lww.com
Traumatic brain injury is a complex disease, and development of clinically effective
neuroprotective agents is a difficult task. Experimental traumatic brain injury has provided …
neuroprotective agents is a difficult task. Experimental traumatic brain injury has provided …
Neuropharmacology in traumatic brain injury: from preclinical to clinical neuroprotection?
D Lerouet, C Marchand‐Leroux… - Fundamental & clinical …, 2021 - Wiley Online Library
Traumatic brain injury (TBI) constitutes a major health problem worldwide and is a leading
cause of death and disability in individuals, contributing to devastating socioeconomic …
cause of death and disability in individuals, contributing to devastating socioeconomic …
Neuroprotection in acute brain injury: an up-to-date review
N Stocchetti, FS Taccone, G Citerio, PE Pepe… - Critical care, 2015 - Springer
Neuroprotective strategies that limit secondary tissue loss and/or improve functional
outcomes have been identified in multiple animal models of ischemic, hemorrhagic …
outcomes have been identified in multiple animal models of ischemic, hemorrhagic …
Neuroprotection trials in traumatic brain injury
S Chakraborty, B Skolnick, RK Narayan - Current neurology and …, 2016 - Springer
Traumatic brain injury (TBI) is a significant cause of mortality and morbidity worldwide.
Current treatment of acute TBI includes surgical intervention when needed, followed by …
Current treatment of acute TBI includes surgical intervention when needed, followed by …
Exploring new routes for neuroprotective drug development in traumatic brain injury
T Janowitz, DK Menon - Science translational medicine, 2010 - science.org
Worldwide, traumatic brain injury (TBI) is a major cause of mortality and morbidity with a
substantial predicted increase in incidence. Despite an obvious need, there are no …
substantial predicted increase in incidence. Despite an obvious need, there are no …